[HTML][HTML] Adipose tissue as a site of toxin accumulation

E Jackson, R Shoemaker, N Larian… - Comprehensive …, 2017 - ncbi.nlm.nih.gov
We examine the role of adipose tissue, typically considered an energy storage site, as a
potential site of toxicant accumulation. Although the production of most persistent organic …

Polychlorinated biphenyls (PCBs): risk factors for autism spectrum disorder?

HK Panesar, CL Kennedy, KP Keil Stietz, PJ Lein - Toxics, 2020 - mdpi.com
Autism spectrum disorder (ASD) includes a group of multifactorial neurodevelopmental
disorders defined clinically by core deficits in social reciprocity and communication …

[图书][B] Late lessons from early warnings: the precautionary principle 1896-2000

P Harremoës, D Gee, M MacGarvin, A Stirling, J Keys… - 2001 - iatp.org
The task of the European Environment Agency (EEA) is to provide information of direct use
for improving decision-making and public participation. We often provide information in …

Prenatal exposure to organohalogens, including brominated flame retardants, influences motor, cognitive, and behavioral performance at school age

E Roze, L Meijer, A Bakker… - Environmental …, 2009 - ehp.niehs.nih.gov
Background Organohalogen compounds (OHCs) are known to have neurotoxic effects on
the developing brain. Objective We investigated the influence of prenatal exposure to OHCs …

[图书][B] The precautionary principle in the 20th century: Late lessons from early warnings

P Harremoes, D Gee, M MacGarvin, A Stirling, J Keys… - 2013 - api.taylorfrancis.com
The precautionary principle is widely seen as fundamental to successful policies for
sustainability. It has been cited in international courts and trade disputes between the USA …

Placenta and fetal brain share a neurodevelopmental disorder DNA methylation profile in a mouse model of prenatal PCB exposure

BI Laufer, K Neier, AE Valenzuela, DH Yasui… - Cell reports, 2022 - cell.com
Polychlorinated biphenyls (PCBs) are developmental neurotoxicants implicated as
environmental risk factors for neurodevelopmental disorders (NDDs). Here, we report the …

Developmental exposure of rats to a reconstituted PCB mixture or aroclor 1254: effects on organ weights, aromatase activity, sex hormone levels, and sweet …

J Hany, H Lilienthal, A Sarasin, A Roth-Härer… - Toxicology and applied …, 1999 - Elsevier
Polychlorinated biphenyls (PCBs) are lipophilic industrial chemicals which are regularly
detected in human breast milk, serum, and tissues. They possess hormone-modulating …

Estrogenic endocrine disrupting chemicals influencing NRF1 regulated gene networks in the development of complex human brain diseases

M Preciados, C Yoo, D Roy - International journal of molecular sciences, 2016 - mdpi.com
During the development of an individual from a single cell to prenatal stages to adolescence
to adulthood and through the complete life span, humans are exposed to countless …

Endocrine-disrupting actions of PCBs on brain development and social and reproductive behaviors

MR Bell - Current Opinion in Pharmacology, 2014 - Elsevier
Highlights•Polychlorinated biphenyls affect a range of social and reproductive
behaviors.•Effects may be mediated via hormonal, dopaminergic, and/or glutamateric …

Levels and chiral signatures of persistent organochlorine pollutants in human tissues from Belgium

S Chu, A Covaci, P Schepens - Environmental Research, 2003 - Elsevier
Polychlorinated biphenyls (PCBs) and organochlorine pesticides (OCPs) were measured in
human tissue samples including muscle, liver, brain, and kidney. The samples were …