Human bodies collectively turn over about 200 billion to 300 billion cells every day. Such
turnover is an integral part of embryonic and postnatal development, as well as routine …

The Adhesion family forms a large branch of the pharmacologically important superfamily of
G protein–coupled receptors (GPCRs). As Adhesion GPCRs increasingly receive attention …

Adhesion G protein-coupled receptors (aGPCRs) constitute an evolutionarily ancient family
of receptors that often undergo autoproteolysis to produce α and β subunits,–. A tethered …

Adhesion G protein–coupled receptors (AGPCRs) are a thirty-three-member subfamily of
Class B GPCRs that control a wide array of physiological processes and are implicated in …

Engulfment and subsequent degradation of apoptotic cells is an essential step that occurs
throughout life in all multicellular organisms,,. ELMO/Dock180/Rac proteins are a conserved …

RTN4-binding proteins were widely studied as" NoGo" receptors, but their physiological
interactors and roles remain elusive. Similarly, BAI adhesion-GPCRs were associated with …

The G protein‐coupled receptor (GPCR) Proteolysis Site (GPS) of cell‐adhesion GPCRs
and polycystic kidney disease (PKD) proteins constitutes a highly conserved autoproteolysis …

Adhesion-type heterotrimeric guanine nucleotide–binding protein (G protein)–coupled
receptors (Adhesion-GPCRs) comprise a class of widely distributed seven-transmembrane …

Glioblastoma multiforme (GBM) is characterized by exuberant angiogenesis, a key event in
tumor growth and progression. The pathologic mechanisms driving this change and the …

The p53 tumor suppressor protein has long been recognized as the central factor protecting
humans from cancer. It has been famously dubbed “the guardian of the genome” due to its …