Epidemiology and burden of human papillomavirus and related diseases, molecular pathogenesis, and vaccine evaluation

AJ Kombe Kombe, B Li, A Zahid, HM Mengist… - Frontiers in public …, 2021 - frontiersin.org
Diagnosed in more than 90% of cervical cancers, the fourth deadliest cancer in women,
human papillomavirus (HPV) is currently the most common pathogen responsible for female …

MicroRNA let-7 and viral infections: focus on mechanisms of action

A Letafati, S Najafi, M Mottahedi, M Karimzadeh… - Cellular & Molecular …, 2022 - Springer
MicroRNAs (miRNAs) are fundamental post-transcriptional modulators of several critical
cellular processes, a number of which are involved in host defense mechanisms. In …

A current update on human papillomavirus-associated head and neck cancers

E Tumban - Viruses, 2019 - mdpi.com
Human papillomavirus (HPV) infection is the cause of a growing percentage of head and
neck cancers (HNC); primarily, a subset of oral squamous cell carcinoma, oropharyngeal …

Pathogenic role of exosomes and microRNAs in HPV‐mediated inflammation and cervical cancer: a review

J Sadri Nahand, M Moghoofei… - … journal of cancer, 2020 - Wiley Online Library
Cervical cancer (CC) is the fourth most common cause of cancer death in women. The most
important risk factor for the development of CC is cervical infection with human papilloma …

Chronic inflammation: key player and biomarker-set to predict and prevent cancer development and progression based on individualized patient profiles

S Qian, O Golubnitschaja, X Zhan - Epma Journal, 2019 - Springer
A strong relationship exists between tumor and inflammation, which is the hot point in cancer
research. Inflammation can promote the occurrence and development of cancer by …

Spatial transcriptomics prediction from histology jointly through transformer and graph neural networks

Y Zeng, Z Wei, W Yu, R Yin, Y Yuan, B Li… - Briefings in …, 2022 - academic.oup.com
The rapid development of spatial transcriptomics allows the measurement of RNA
abundance at a high spatial resolution, making it possible to simultaneously profile gene …

Tracking HPV infection, associated cancer development, and recent treatment efforts—a comprehensive review

S Malik, R Sah, K Muhammad, Y Waheed - Vaccines, 2023 - mdpi.com
Human papillomaviruses (HPVs) are high-risk causative factors for HPV infection. This
infection does not come alone; it is often seen with co-infection with other viruses and acts …

Targeting 7-dehydrocholesterol reductase integrates cholesterol metabolism and IRF3 activation to eliminate infection

J Xiao, W Li, X Zheng, L Qi, H Wang, C Zhang, X Wan… - Immunity, 2020 - cell.com
Recent work suggests that cholesterol metabolism impacts innate immune responses
against infection. However, the key enzymes or the natural products and mechanisms …

The role of miR‐146a in viral infection

JS Nahand, MR Karimzadeh, M Nezamnia… - IUBMB …, 2020 - Wiley Online Library
Cellular microRNAs (miRNAs) were identified as a key player in the posttranscriptional
regulation of cellular‐genes regulatory pathways. They also emerged as a significant …

Breast cancer risk and human papillomavirus infection: a Bradford Hill criteria based evaluation

M Usman, Y Hameed, M Ahmad… - Infectious Disorders …, 2022 - benthamdirect.com
Background: The association between human papillomavirus (HPV) and human breast
cancer (BC) has already been thoroughly studied worldwide with contradictory findings …