Acute optic neuritis is the most common optic neuropathy affecting young adults. Exciting
developments have occurred over the past decade in understanding of optic neuritis …

Clinically isolated syndrome (CIS) is a term that describes a first clinical episode with
features suggestive of multiple sclerosis (MS). It usually occurs in young adults and affects …

Due to the heterogeneous nature of the disease, it is a challenge to capture disease activity
of multiple sclerosis (MS) in a reliable and valid way. Therefore, it can be difficult to assess …

Optical coherence tomography (OCT) is a new method that could aid analysis of
neurodegeneration in multiple sclerosis (MS) by capturing thinning of the retinal nerve fibre …

There has been growing interest in the use of retinal imaging for tracking disease
progression in multiple sclerosis. However, systematic and detailed pathological …

PURPOSE: To examine the relation of visual function to retinal nerve fiber layer (RNFL)
thickness as a structural biomarker for axonal loss in multiple sclerosis (MS), and to compare …

Objective To determine to what degree changes in retinal nerve fiber layer (RNFL) thickness
after optic neuritis (ON) correlate with either visual recovery or impairment. Methods ON can …

Post-mortem ganglion cell dropout has been observed in multiple sclerosis; however,
longitudinal in vivo assessment of retinal neuronal layers following acute optic neuritis …

Visual impairment is a key manifestation of multiple sclerosis. Acute optic neuritis is a
common, often presenting manifestation, but visual deficits and structural loss of retinal …

Optic nerve disorders encompass a wide spectrum of conditions characterized by the loss of
retinal ganglion cells (RGCs) and subsequent degeneration of the optic nerve. The etiology …