Cannabinoid Signaling in the Skin: Therapeutic Potential of the “C (ut) annabinoid” System

KF Tóth, D Ádám, T Bíró, A Oláh - Molecules, 2019 - mdpi.com
The endocannabinoid system (ECS) has lately been proven to be an important, multifaceted
homeostatic regulator, which influences a wide-variety of physiological processes all over …

Possible use of phytochemicals for recovery from COVID-19-induced anosmia and ageusia

S Koyama, K Kondo, R Ueha, H Kashiwadani… - International Journal of …, 2021 - mdpi.com
The year 2020 became the year of the outbreak of coronavirus, SARS-CoV-2, which
escalated into a worldwide pandemic and continued into 2021. One of the unique symptoms …

Neuroprotective and immunomodulatory action of the endocannabinoid system under neuroinflammation

LA Kasatkina, S Rittchen, EM Sturm - International Journal of Molecular …, 2021 - mdpi.com
Endocannabinoids (eCBs) are lipid-based retrograde messengers with a relatively short half-
life that are produced endogenously and, upon binding to the primary cannabinoid receptors …

Medicinal Chemistry, Pharmacology, and Potential Therapeutic Benefits of Cannabinoid CB2 Receptor Agonists

M Aghazadeh Tabrizi, PG Baraldi, PA Borea… - Chemical …, 2016 - ACS Publications
The endocannabinoid system is represented by a group of neuromodulatory lipids and their
receptors that are involved in a variety of physiological and pathological conditions. The …

Peripheral mechanisms of neuropathic pain—the role of neuronal and non-neuronal interactions and their implications for topical treatment of neuropathic pain

M Kocot-Kępska, R Zajączkowska, J Mika… - Pharmaceuticals, 2021 - mdpi.com
Neuropathic pain in humans arises as a consequence of injury or disease of somatosensory
nervous system at peripheral or central level. Peripheral neuropathic pain is more common …

Joints for joints: cannabinoids in the treatment of rheumatoid arthritis

T Lowin, M Schneider, G Pongratz - Current opinion in …, 2019 - journals.lww.com
Cannabinoids might be a suitable treatment for RA, but it is important to target the right
receptors in the right place. For clinical studies, we propose a combination of a CB 2 agonist …

Endogenous opiates and behavior: 2016

RJ Bodnar - Peptides, 2018 - Elsevier
This paper is the thirty-ninth consecutive installment of the annual review of research
concerning the endogenous opioid system. It summarizes papers published during 2016 …

[HTML][HTML] Autism and associated disorders: cannabis as a potential therapy

M Babayeva, H Assefa, P Basu… - Frontiers in Bioscience …, 2022 - imrpress.com
Autism spectrum disorder (ASD) is a group of disabilities with impairments in physical,
verbal, and behavior areas. Regardless the growing frequency of autism, no medicine has …

A peripheral CB2 cannabinoid receptor mechanism suppresses chemotherapy-induced peripheral neuropathy: evidence from a CB2 reporter mouse

X Lin, Z Xu, L Carey, J Romero, A Makriyannis… - Pain, 2022 - journals.lww.com
Abstract CB2 cannabinoid receptors (CB2) are a promising therapeutic target that lacks
unwanted side effects of CB1 activation. However, the cell types expressing CB2 that …

[HTML][HTML] The antinociceptive activity and mechanism of action of cannabigerol

Y Wen, Z Wang, R Zhang, Y Zhu, G Lin, R Li… - Biomedicine & …, 2023 - Elsevier
Cannabis has been used for centuries to treat pain. The antinociceptive activity of
tetrahydrocannabinol (THC) or cannabidiol (CBD) has been widely studied. However, the …