Pain measures traditionally used in rodents record mere reflexes evoked by sensory stimuli;
the results thus may not fully reflect the human pain phenotype. Alterations in physical and …

The incidence of pediatric cancers is rising steadily across the world, along with the
challenges in understanding the molecular mechanisms and devising effective therapeutic …

Intervertebral disc (IVD) degeneration is characterized by decreased cellularity and
proteoglycan synthesis and increased inflammation, catabolism, and neural/vascular …

Adiponectin, a hormone secreted by adipocytes, has anti-inflammatory effects and is
involved in various physiological and pathological processes such as obesity, inflammatory …

To investigate whether TP53‐induced glycolysis and apoptosis regulator (TIGAR)
participates in compression‐induced intervertebral disc (IVD) degeneration, and to …

Although degenerative disc disease (DDD) and related low back pain (LBP) are growing
public health problems, the underlying disease mechanisms remain unclear. An increase in …

Sheep are one of the many animal models used to investigate the pathophysiology of disc
degeneration and the regenerative strategies for intervertebral disc (IVD) disease. To date …

Simple Summary Using a mouse model of breast cancer driven by the mammary epithelial
expression of the polyoma middle T oncoprotein in which the tumors progress from benign …

There are many kinds of therapy for patients with pain in cancer; one of those is the third-
class fentanyl. However, the identification of the use patterns (dosage and frequency of use) …