Changes in glutathione content in liver diseases: an update

M Vairetti, LG Di Pasqua, M Cagna, P Richelmi… - Antioxidants, 2021 - mdpi.com
Glutathione (GSH), a tripeptide particularly concentrated in the liver, is the most important
thiol reducing agent involved in the modulation of redox processes. It has also been …

[HTML][HTML] MicroRNAs in the regulation of cellular redox status and its implications in myocardial ischemia-reperfusion injury

T Carbonell, AV Gomes - Redox biology, 2020 - Elsevier
MicroRNAs (miRNAs) are small RNAs that do not encode for proteins and play key roles in
the regulation of gene expression. miRNAs are involved in a comprehensive range of …

Silver nanoparticles induce oxidative cell damage in human liver cells through inhibition of reduced glutathione and induction of mitochondria-involved apoptosis

MJ Piao, KA Kang, IK Lee, HS Kim, S Kim, JY Choi… - Toxicology letters, 2011 - Elsevier
Silver nanoparticles (AgNPs), which have well-known antimicrobial properties, are
extensively used in various medical and general applications. Despite the widespread use …

New insights into the cellular and molecular mechanisms of cold storage injury

U Rauen, H de Groot - Journal of investigative medicine, 2004 - journals.sagepub.com
Solid organ grafts, but also other biologic materials requiring storage for a few hours to a few
days, are usually stored under hypothermic conditions. To decrease graft injury during cold …

Glutathione induced immune-stimulatory activity by promoting M1-like macrophages polarization via potential ROS scavenging capacity

DH Kwon, H Lee, C Park, SH Hong, SH Hong, GY Kim… - Antioxidants, 2019 - mdpi.com
The present study investigated the immunomodulatory activity of reduced glutathione (GSH)
by assessment of the macrophage polarization (MP)-mediated immune response in RAW …

[HTML][HTML] Integrated molecular signaling involving mitochondrial dysfunction and alteration of cell metabolism induced by tyrosine kinase inhibitors in cancer

MA Rodríguez-Hernández, P de la Cruz-Ojeda… - Redox Biology, 2020 - Elsevier
Cancer cells have unlimited replicative potential, insensitivity to growth-inhibitory signals,
evasion of apoptosis, cellular stress, and sustained angiogenesis, invasiveness and …

[HTML][HTML] Genome multiplication as adaptation to tissue survival: evidence from gene expression in mammalian heart and liver

OV Anatskaya, AE Vinogradov - Genomics, 2007 - Elsevier
To elucidate the functional significance of genome multiplication in somatic tissues, we
performed a large-scale analysis of ploidy-associated changes in expression of non-tissue …

Mammalian cell injury induced by hypothermia the emerging role for reactive oxygen species

U Rauen, H Groot - 2002 - degruyter.com
Hypothermia is a wellknown strategem to protect biological material against injurious or
degradative processes and is widely used in experimental and especially in clinical …

Liproxstatin-1 Alleviates Lung Transplantation-induced Cold Ischemia–Reperfusion Injury by Inhibiting Ferroptosis

J Zhao, J Li, D Wei, F Gao, X Yang, B Yue… - …, 2023 - journals.lww.com
Background. Primary graft dysfunction, which is directly related to cold ischemia–reperfusion
(CI/R) injury, is a major obstacle in lung transplantation (LTx). Ferroptosis, a novel mode of …

Phloroglucinol (1, 3, 5-trihydroxybenzene) protects against ionizing radiation-induced cell damage through inhibition of oxidative stress in vitro and in vivo

KA Kang, R Zhang, S Chae, SJ Lee, J Kim, J Kim… - Chemico-biological …, 2010 - Elsevier
Exposure of cells to γ-rays induces the production of reactive oxygen species (ROS) that
play a main role in ionizing radiation damage. We have investigated the radioprotective …