Polyethylene glycol or PEG has a long history of use in medicine. Many conventional
formulations utilize PEG as either an active ingredient or an excipient. PEG found its use in …

Conjugation of polyethylene glycols (PEGs) to proteins or drug delivery nanosystems is a
widely accepted method to increase the therapeutic index of complex nano …

Nucleic acid aptamers, often termed'chemical antibodies', are functionally comparable to
traditional antibodies, but offer several advantages, including their relatively small physical …

Aptamers are nucleic acid molecules that mimic antibodies by folding into complex 3D
shapes that bind to specific targets. Although some aptamers exist naturally as the ligand …

Antiplatelet agents and anticoagulants are a mainstay for the prevention and treatment of
thrombosis. However, despite advances in antithrombotic therapy, a fundamental challenge …

Polyethylene glycol (PEG) is a flexible, hydrophilic simple polymer that is physically attached
to peptides, proteins, nucleic acids, liposomes, and nanoparticles to reduce renal clearance …

Aptamers are single-stranded nucleic acid molecules that bind to and inhibit proteins and
are commonly produced by systematic evolution of ligands by exponential enrichment …

Nanomedicines and macromolecular drugs can induce hypersensitivity reactions (HSRs)
with symptoms ranging from flushing and breathing difficulties to hypothermia, hypotension …

Polyethylene glycol (PEG)-coated nanopharmaceuticals can cause mild to severe
hypersensitivity reactions (HSRs), which can occasionally be life threatening or even lethal …

Aptamers have come in the spotlight as bio-mimetic molecular recognition elements in the
field of biomedicine due to various applications in diagnostics, drug delivery, therapeutics …