Recent advances have uncovered a previously unknown function of vitamin C in epigenetic
regulation. Vitamin C exists predominantly as an ascorbate anion under physiological pH …

Somatic cell nuclear transfer (SCNT) has been an area of interest in the field of stem cell
research and regenerative medicine for the past 20 years. The main biological goal of SCNT …

Contents The aim of this study was to assess the effects of different antioxidants on the
levels of reactive oxygen species (ROS) and glutathione (GSH) in oocytes during in vitro …

In vitro follicle growth and oocyte maturation still has a series of limitations, since not all
oocytes matured in vitro have the potential to develop in viable embryos. One of the factors …

L-ascorbic acid (Vitamin C) can enhance the meiotic maturation and developmental
competence of porcine oocytes, but the underlying molecular mechanism remains obscure …

Mammalian oocytes can reprogram differentiated somatic cells into a totipotent state through
somatic cell nuclear transfer (SCNT), which is known as cloning. Although many mammalian …

The low full-term developmental efficiency of porcine somatic cell nuclear transfer (SCNT)
embryos is mainly attributed to imperfect epigenetic reprogramming in the early embryos …

The ability to control the transition from an undifferentiated stem cell to a specific cell fate is
one of the key techniques that are required for the application of interventional technologies …

Animal cloning has been achieved in many species by transplanting differentiated cell
nuclei to unfertilized oocytes. However, the low efficiencies of cloning have remained an …

Which comes first: tissue structure or cell differentiation? Although different cell types
establish distinct structures delineating the inside and outside of an embryo, they …