Biomechanics of collective cell migration in cancer progression: experimental and computational methods
Cell migration is essential for regulating many biological processes in physiological or
pathological conditions, including embryonic development and cancer invasion. In vitro and …
pathological conditions, including embryonic development and cancer invasion. In vitro and …
Probing Multicellular Tissue Fusion of Cocultured Spheroids—A 3D‐Bioassembly Model
GCJ Lindberg, X Cui, M Durham… - Advanced …, 2021 - Wiley Online Library
While decades of research have enriched the knowledge of how to grow cells into mature
tissues, little is yet known about the next phase: fusing of these engineered tissues into …
tissues, little is yet known about the next phase: fusing of these engineered tissues into …
Alteration in cartilage matrix stiffness as an indicator and modulator of osteoarthritis
J Song, X Zeng, C Li, H Yin, S Mao, D Ren - Bioscience Reports, 2024 - portlandpress.com
Osteoarthritis (OA) is characterized by cartilage degeneration and destruction, leading to
joint ankylosis and disability. The major challenge in diagnosing OA at early stage is not …
joint ankylosis and disability. The major challenge in diagnosing OA at early stage is not …
Chloride channel and inflammation-mediated pathogenesis of osteoarthritis
Z Lin, Z Deng, J Liu, Z Lin, S Chen… - Journal of Inflammation …, 2022 - Taylor & Francis
Articular cartilage allows the human body to buffer and absorb stress during normal
exercise. It is mainly composed of cartilage cells and the extracellular matrix and is …
exercise. It is mainly composed of cartilage cells and the extracellular matrix and is …
Investigation of cell-substrate adhesion properties of living chondrocyte by measuring adhesive shear force and detachment using AFM and inverse FEA
It is well-known that cell adhesion is important in many biological processes such as cell
migration and proliferation. A better understanding of the cell adhesion process will shed …
migration and proliferation. A better understanding of the cell adhesion process will shed …
Effect of substrate stiffness on mechanical coupling and force propagation at the infarct boundary
DT Nguyen, N Nagarajan, P Zorlutuna - Biophysical journal, 2018 - cell.com
Heterogeneous intercellular coupling plays a significant role in mechanical and electrical
signal transmission in the heart. Although many studies have investigated the electrical …
signal transmission in the heart. Although many studies have investigated the electrical …
Cellular volume regulation and substrate stiffness modulate the detachment dynamics of adherent cells
Quantitative characterizations of cell detachment are vital for understanding the fundamental
mechanisms of cell adhesion. Experiments have found that cell detachment shows strong …
mechanisms of cell adhesion. Experiments have found that cell detachment shows strong …
Cell mechanics: Are poroviscoelastic parameters reliable?
B Klahr, OT Pinto, TA Carniel, EA Fancello - Mechanics Research …, 2021 - Elsevier
Motivated by a literature survey on the mechanical characterization of single cells by
biphasic models, the present study seeks to answer if the large dispersion on the …
biphasic models, the present study seeks to answer if the large dispersion on the …
An open-source combined atomic force microscope and optical microscope for mechanobiology studies
Abstract Atomic Force Microscopy (AFM) has become the gold standard tool for measuring
mechanical properties of biological samples including proteins, single cells and tissues …
mechanical properties of biological samples including proteins, single cells and tissues …
[HTML][HTML] Poroelastic osmoregulation of living cell volume
Cells maintain their volume through fine intracellular osmolarity regulation. Osmotic
challenges drive fluid into or out of cells causing swelling or shrinkage, respectively. The …
challenges drive fluid into or out of cells causing swelling or shrinkage, respectively. The …