Ultrasmall nanoparticles are often grouped under the broad umbrella term of “nanoparticles”
when reported in the literature. However, for biomedical applications, their small sizes give …

Drug delivery across the blood–brain barrier (BBB) is one of the biggest challenges in
modern medicine due to the BBB's highly semipermeable property that limits most …

Carbon-based nanomaterials have established a prime position as drug delivery carriers. It
is very interesting to see that a carbon nanostructure could be used as a drug too, instead of …

Neurofibrillary tangle, composed of aggregated tau protein, is a pathological hallmark of
Alzheimer's disease (AD). The inhibition of tau aggregation is therefore an important …

Regenerative medicine aims to engineer tissue constructs that can recapitulate the
functional and structural properties of native organs. Most novel regenerative therapies are …

Quantum dots (QDs) are semiconductor nanocrystals possessing unique optoelectrical
properties in that they can emit light energy of specific tunable wavelengths when excited by …

Nanoparticles (NPs) based therapies for Alzheimer's disease (AD) attract interest due to
their ability to pass across or bypass the blood‐brain barrier. Chitosan (CS) NPs or …

The blood–brain barrier (BBB) is a tailored system of capillary endothelial cells intermixed
with tight junctions and adherent junctions that regulates the transport of various materials …

Paracellular permeability across epithelial and endothelial cells is, in large part, regulated
by apical intercellular junctions also referred to as tight junctions (TJs). These junctions …

Antioxidants are a class of molecules with an innate affinity to neutralize reactive oxygen
species (ROS), which are known to cause oxidative stress. Oxidative stress has been …