Extracellular vehicles (EVs) are a heterogeneous group of cell and membranous particles
originating from different cell compartments. EVs participate in many essential physiological …

The vertebrate brain and spinal cord arise from a common precursor, the neural tube, which
forms very early during embryonic development. To shape the forming neural tube, changes …

Spina bifida (SB) is a debilitating birth defect caused by multiple gene and environment
interactions. Though SB shows non-Mendelian inheritance, genetic factors contribute to an …

Neural tube defects are dreadful congenital deformities of the nervous system that occur
owing to failure of normal neural tube closure. Genetic and non-genetic factors contribute to …

Background Maternal smoking or passive smoking during gestation increases the risk of
congenital birth defects, including neural tube defects (NTDs). Cigarette smoke is a …

Background Neural tube defects (NTDs) are among the most common and severe
congenital defects in humans. Their genetic etiology is complex and remains poorly …

Background: Neural tube defects are a major public health problem and substantially
contribute to morbidity and mortality, particularly in low-income countries, including Ethiopia …

Background Human studies of genetic risk factors for neural tube defects, severe birth
defects associated with long‐term health consequences in surviving children, have …

Neural tube defects (NTDs) are severe malformations of the central nervous system that
arise from failure of neural tube closure. HECTD1 is an E3 ubiquitin ligase required for …

Abstract Spina Bifida (SB) and Wilm's Tumor (WT) are conditions, both associated with
children. Several studies have shown that WT later develops in SB patients, which led us to …