Gene drives are selfish genetic elements that are transmitted to progeny at super-Mendelian
(> 50%) frequencies. Recently developed CRISPR–Cas9-based gene-drive systems are …

Mosquitoes bring global health problems by transmitting parasites and viruses such as
malaria and dengue. Unfortunately, current insecticide-based control strategies are only …

The origin story and emergence of molecular biology is muddled. The early triumphs in
bacterial genetics and the complexity of animal and plant genomes complicate an intricate …

Genetic biocontrol aims to suppress or modify populations of species to protect public
health, agriculture, and biodiversity. Advancements in genome engineering technologies …

A recurring target-site mutation identified in various pests and disease vectors alters the
voltage gated sodium channel (vgsc) gene (often referred to as knockdown resistance or …

Gene drives are engineered alleles that can bias inheritance in their favor, allowing them to
spread throughout a population. They could potentially be used to modify or suppress pest …

Cancer vaccines hold considerable promise for the immunotherapy of solid tumors.
Nanomedicine offers several strategies for enhancing vaccine effectiveness. In particular …

Interest in gene drive technology has continued to grow as promising new drive systems
have been developed in the lab and discussions are moving towards implementing field …

Background Homing gene drives hold great promise for the genetic control of natural
populations. However, current homing systems are capable of spreading uncontrollably …

CRISPR-based gene drives have the potential to spread within populations and are
considered as promising vector control tools. A doublesex-targeting gene drive was able to …