Satellite cells are adult myogenic stem cells that repair damaged muscle. The enduring
capacity for muscle regeneration requires efficient satellite cell expansion after injury, their …

Growth differentiation factor 11 (GDF11) and myostatin (or GDF8) are closely related
members of the transforming growth factor β superfamily and are often perceived to serve …

Importance Precise stratification of cardiovascular risk in patients with coronary heart
disease (CHD) is needed to inform treatment decisions. Objective To derive and validate a …

A reliable, individualized, and dynamic surrogate of cardiovascular risk, synoptic for key
biologic mechanisms, could shorten the path for drug development, enhance drug cost …

Circular RNAs (circRNAs) are expressed at high levels in the brain and are involved in
various central nervous system diseases. However, the potential role of circRNAs in …

Growth and differentiation factor 11 (GDF11) is a transforming growth factor β superfamily
member with a controversial role in aging processes. We have developed a highly specific …

Rationale: Growth differentiation factor 11 (GDF11) and GDF8 are members of the
transforming growth factor-β superfamily sharing 89% protein sequence homology. We have …

Plasma biomarkers that reflect molecular states of the cardiovascular system are central for
clinical decision making. Routinely used plasma biomarkers include troponins, natriuretic …

As the elderly segment of the world population increases, it is critical to understand the
changes in cardiac structure and function during the normal aging process. In this review …

Heart failure (HF) is a global medical problem that characterizes poor prognosis and high
economic burden for the health system and family of the HF patients. Although modern …