Neurodegenerative diseases are among the most common causes of disability worldwide.
Although neurodegenerative diseases are heterogeneous in both their clinical features and …

Alzheimer's disease (AD) was discovered and the pathological hallmarks were revealed
more than a century ago. Subsequently, many remarkable discoveries and breakthroughs …

Background Alternations in gut microbiota and a number of genes have been implicated as
risk factors for the development of Alzheimer disease (AD). However, the interactions …

Alzheimer's disease (AD) is the most common neurodegenerative disease caused by
eventually aggregated amyloid β (Aβ) plaques in degenerating neurons of the aging brain …

Novel drug development is onerous, time consuming and overpriced process with
particularly low success and relatively high enfeebling rates. To overcome this burden, drug …

Alterations in metabolic parameters have been associated with an increased risk of
dementia, among which thyroid function has gained great importance in Alzheimer's disease …

Alzheimer's disease (AD) is the most common type of dementia and affects millions of
people worldwide. Since complex diseases are often the result of combinations of gene …

Alzheimer's disease (AD) is a heterogeneous disorder with multiple patterns of clinical
manifestations. Recently, due to the advance of linkage studies, next‐generation …

472a Wednesday, February 22, 2023 profiles. The possible associations of selected drugs
with AD related genes were predicted by pharmacogenomics analysis and confirmed …

Proteins are tiny players involved in the activation and deactivation of multiple signaling
cascades through interactions in cells. The TNFR1 and MADD interact with each other and …