A central aim of cancer research has been to identify the mutated genes that are causally
implicated in oncogenesis ('cancer genes'). After two decades of searching, how many have …

Horizontal genomics is a new field in prokaryotic biology that is focused on the analysis of
DNA sequences in prokaryotic chromosomes that seem to have originated from other …

Recently, we reported the discovery of three novel coronaviruses, bulbul coronavirus
HKU11, thrush coronavirus HKU12, and munia coronavirus HKU13, which were identified …

Abstract The Orientations of Proteins in Membranes (OPM) database is a curated web
resource that provides spatial positions of membrane-bound peptides and proteins of known …

Recently developed methods have shown considerable promise in predicting residue–
residue contacts in protein 3D structures using evolutionary covariance information …

Ribosome-footprint profiling provides genome-wide snapshots of translation, but technical
challenges can confound its analysis. Here, we use improved methods to obtain ribosome …

WebLogo generates sequence logos, graphical representations of the patterns within a
multiple sequence alignment. Sequence logos provide a richer and more precise …

To provide the scientific community with a single, centralized, authoritative resource for
protein sequences and functional information, the Swiss‐Prot, TrEMBL and PIR protein …

In the genomic era, one of the fundamental goals is to characterize the function of proteins
on a large scale. We describe a method, PANTHER, for relating protein sequence …

The parasite Plasmodium falciparum is responsible for hundreds of millions of cases of
malaria, and kills more than one million African children annually. Here we report an …