Computationally designed protein nanoparticles have recently emerged as a promising
platform for the development of new vaccines and biologics. For many applications …

Global containment of COVID-19 still requires accessible and affordable vaccines for low-
and middle-income countries (LMICs). Recently approved vaccines provide needed …

In the past decade, new approaches to the discovery and development of vaccines have
transformed the field. Advances during the COVID‐19 pandemic allowed the production of …

Global containment of COVID-19 still requires accessible and affordable vaccines for low-
and middle-income countries (LMICs). 1 Recently approved vaccines provide needed …

Porcine rotaviruses (PoRVs) cause severe economic losses in the swine industry. P [7] and
P [23] are the predominant genotypes circulating on farms, but no vaccine is yet available …

A two-step developability assessment workflow is described to screen variants of
recombinant protein antigens under various formulation conditions to rapidly identify stable …

In a companion paper, a two-step developability assessment is presented to rapidly
evaluate low-cost formulations (multi-dose, aluminum-adjuvanted) for new subunit vaccine …

Developing media to sustain cell growth and production is an essential and ongoing activity
in bioprocess development. Modifications to media can often address host or product …

Background Komagataella phaffii is a commonly used alternative host for manufacturing
therapeutic proteins, in part because of its ability to secrete recombinant proteins into the …

Analytical characterization of proteins is a critical task for developing therapeutics and
subunit vaccine candidates. Assessing candidates with a battery of biophysical assays can …