Toolbox for distal C–H bond functionalizations in organic molecules

SK Sinha, S Guin, S Maiti, JP Biswas, S Porey… - Chemical …, 2021 - ACS Publications
Transition-metal-catalyzed C–H activation has developed a contemporary approach to the
omnipresent area of retrosynthetic disconnection. Scientific researchers have been tempted …

Metal-catalysed C–H bond activation and borylation

R Bisht, C Haldar, MMM Hassan, ME Hoque… - Chemical Society …, 2022 - pubs.rsc.org
Transition metal-catalysed direct borylation of hydrocarbons via C–H bond activation has
received a remarkable level of attention as a popular reaction in the synthesis of …

Transition metal catalysis controlled by hydrogen bonding in the second coordination sphere

JNH Reek, B de Bruin, S Pullen, TJ Mooibroek… - Chemical …, 2022 - ACS Publications
Transition metal catalysis is of utmost importance for the development of sustainable
processes in academia and industry. The activity and selectivity of metal complexes are …

[HTML][HTML] A comprehensive overview of directing groups applied in metal-catalysed C–H functionalisation chemistry

C Sambiagio, D Schönbauer, R Blieck… - Chemical Society …, 2018 - pubs.rsc.org
The present review is devoted to summarizing the recent advances (2015–2017) in the field
of metal-catalysed group-directed C–H functionalisation. In order to clearly showcase the …

Strategic evolution in transition metal-catalyzed directed C–H bond activation and future directions

S Rej, A Das, N Chatani - Coordination Chemistry Reviews, 2021 - Elsevier
In the field of C–H bond functionalization chemistry, directed C–H bond activation strategies
are highly appreciated due to the high efficiency and selectivity of such reactions towards a …

Transition metal–catalyzed remote C─ H borylation: An emerging synthetic tool

MMM Hassan, S Guria, S Dey, J Das… - Science …, 2023 - science.org
Transition metal–catalyzed C─ H bond activation and borylation is a powerful synthetic
method that offers versatile synthetic transformation from organoboron compounds to …

Achieving site-selectivity for C–H activation processes based on distance and geometry: a carpenter's approach

G Meng, NYS Lam, EL Lucas… - Journal of the …, 2020 - ACS Publications
The ability to differentiate between highly similar C–H bonds in a given molecule remains a
fundamental challenge in organic chemistry. In particular, the lack of sufficient steric and …

Arene diversification through distal C(sp2)−H functionalization

U Dutta, S Maiti, T Bhattacharya, D Maiti - Science, 2021 - science.org
BACKGROUND Organic synthetic chemistry has facilitated the production of medicines,
agrochemicals, food, polymers, dyes, and more through step-and atom-economical …

New horizons for catalysis disclosed by supramolecular chemistry

G Olivo, G Capocasa, D Del Giudice… - Chemical Society …, 2021 - pubs.rsc.org
The adoption of a supramolecular approach in catalysis promises to address a number of
unmet challenges, ranging from activity (unlocking of novel reaction pathways) to selectivity …

Hydrogen-bond-acceptor ligands enable distal C(sp3)–H arylation of free alcohols

DA Strassfeld, CY Chen, HS Park, DQ Phan, JQ Yu - Nature, 2023 - nature.com
The functionalization of C–H bonds in organic molecules is one of the most direct
approaches for chemical synthesis. Recent advances in catalysis have allowed native …