Highlights•Biofilm development and quorum sensing are social bacterial
behaviours.•Quorum sensing regulates genes involved in biofilm development.•Quorum …

Twenty-five years have passed since the discovery of cyclic dimeric (3′→ 5′) GMP (cyclic
di-GMP or c-di-GMP). From the relative obscurity of an allosteric activator of a bacterial …

Many bacteria swim in liquid or swarm over solid surfaces by synthesizing rotary flagella.
The same bacteria that are motile also commonly form nonmotile multicellular aggregates …

On the stage of bacterial signal transduction and regulation, bis-(3′-5′)-cyclic dimeric
guanosine monophosphate (c-di-GMP) has long played the part of Sleeping Beauty. c-di …

For an organism to survive, it must be able to sense its environment and regulate
physiological processes accordingly. Understanding how bacteria integrate signals from …

Abstract Bis-(3′-5′)-cyclic dimeric GMP (c-di-GMP) is a ubiquitous second messenger that
regulates cell surface-associated traits in bacteria. Components of this regulatory network …

Quorum sensing (QS) is a process of cell-to-cell communication that enables bacteria to
transition between individual and collective lifestyles. QS controls virulence and biofilm …

With the opportunistic pathogen Pseudomonas aeruginosa, quorum sensing based on
homoserine lactones was found to influence biofilm formation. Here we discern a …

Vibrio cholerae can switch between motile and biofilm lifestyles. The last decades have
been marked by a remarkable increase in our knowledge of the structure, regulation, and …

Numerous microorganisms inhabiting harsh niches produce exopolysaccharides as a
significant strategy to survive in extreme conditions. The exopolysaccharides synthesized by …