After their synthesis from cholesterol in hepatic tissues, bile acids (BAs) are secreted into the
intestinal lumen. Most BAs are subsequently re-absorbed in the terminal ileum and are …

Butyrate is a short-chain fatty acid produced by colonic gut bacteria as a result of
fermentation of dietary fibers. In the colon, butyrate is a major energy substrate and …

Dietary fiber (DF) is considered an interventional diet beneficial for human health. High DF
intake effectively reduces the incidence of three major chronic diseases, type 2 diabetes …

Short-chain fatty acids (SCFAs), such as butyrate, propionate, and acetate produced by the
gut microbiota have been implicated in physiological responses (defense mechanisms …

Bile acids are major signaling molecules that play a significant role as emulsifiers in the
digestion and absorption of dietary lipids. Bile acids are amphiphilic molecules produced by …

Colorectal cancer (CRC) is one of the leading causes of mortality for cancer in industrialized
countries. The link between diet and CRC is well-known, and presumably CRC is the type of …

Many chronic diseases are associated with decreased abundance of the gut commensal
Faecalibacterium prausnitzii. This strict anaerobe can grow on dietary fibers, eg, prebiotics …

The release of lysosomal hydrolase into the cytoplasm is accompanied by several systems
of apoptosis signal transduction, and the imbalance between cell viability and apoptosis …

Functional constipation (FC) is a high morbidity gastrointestinal disease for which
dysfunction in the enteric nervous system is a major pathogenesis mechanism. To enhance …

Natural phytochemicals are extensively considered to potentially ameliorate or reverse the
pathological progression of colitis-associated colon cancer (CAC). The present study aimed …