[HTML][HTML] Calling in SYK: SYK's dual role as a tumor promoter and tumor suppressor in cancer
MO Krisenko, RL Geahlen - … et Biophysica Acta (BBA)-Molecular Cell …, 2015 - Elsevier
SYK (spleen tyrosine kinase) is well-characterized in the immune system as an essential
enzyme required for signaling through multiple classes of immune recognition receptors. As …
enzyme required for signaling through multiple classes of immune recognition receptors. As …
Linear and circular PVT1 in hematological malignancies and immune response: two faces of the same coin
Non coding RNAs (ncRNAs) have emerged as regulators of human carcinogenesis by
affecting the expression of key tumor suppressor genes and oncogenes. They are divided …
affecting the expression of key tumor suppressor genes and oncogenes. They are divided …
Genetic and phenotypic attributes of splenic marginal zone lymphoma
F Bonfiglio, A Bruscaggin, F Guidetti… - Blood, The Journal …, 2022 - ashpublications.org
Splenic marginal zone B-cell lymphoma (SMZL) is a heterogeneous clinico-biological entity.
The clinical course is variable, multiple genes are mutated with no unifying mechanism, and …
The clinical course is variable, multiple genes are mutated with no unifying mechanism, and …
Whole-exome sequencing in splenic marginal zone lymphoma reveals mutations in genes involved in marginal zone differentiation
Splenic marginal zone lymphoma (SMZL) is a B-cell neoplasm whose molecular
pathogenesis remains fundamentally unexplained, requiring more precise diagnostic …
pathogenesis remains fundamentally unexplained, requiring more precise diagnostic …
Role of microRNA in proliferation phase of wound healing
Wound healing is a complex biological process that is generally composed of four phases:
hemostasis, inflammation, proliferation, and remodeling. The proliferation phase is crucial …
hemostasis, inflammation, proliferation, and remodeling. The proliferation phase is crucial …
miRNA-based therapies in B cell non-Hodgkin lymphoma
T Fuertes, AR Ramiro, VG de Yebenes - Trends in Immunology, 2020 - cell.com
Non-Hodgkin lymphoma (NHL) is a diverse class of hematological cancers, many of which
arise from germinal center (GC)-experienced B cells. Thus GCs, the sites of antibody affinity …
arise from germinal center (GC)-experienced B cells. Thus GCs, the sites of antibody affinity …
miR‐155 as a biomarker in B‐cell malignancies
H Due, P Svendsen, JS Bødker… - BioMed research …, 2016 - Wiley Online Library
MicroRNAs have the potential to be useful biomarkers in the development of individualized
treatment since they are easy to detect, are relatively stable during sample handling, and are …
treatment since they are easy to detect, are relatively stable during sample handling, and are …
MiR-377 targets E2F3 and alters the NF-kB signaling pathway through MAP3K7 in malignant melanoma
L Zehavi, H Schayek, J Jacob-Hirsch, Y Sidi… - Molecular cancer, 2015 - Springer
Background The incidence of cutaneous malignant melanoma continues to rise, and once
the disease metastasizes it is almost inevitably fatal. We recently reported that a large …
the disease metastasizes it is almost inevitably fatal. We recently reported that a large …
DNA methylation profiling identifies two splenic marginal zone lymphoma subgroups with different clinical and genetic features
AJ Arribas, A Rinaldi, AA Mensah… - Blood, The Journal …, 2015 - ashpublications.org
Splenic marginal zone lymphoma is a rare lymphoma. Loss of 7q31 and somatic mutations
affecting the NOTCH2 and KLF2 genes are the commonest genomic aberrations. Epigenetic …
affecting the NOTCH2 and KLF2 genes are the commonest genomic aberrations. Epigenetic …
MicroRNA-377 suppresses cell proliferation and invasion by inhibiting TIAM1 expression in hepatocellular carcinoma
G Chen, L Lu, C Liu, L Shan, D Yuan - PloS one, 2015 - journals.plos.org
Increasing evidence has suggested that microRNAs (miRNAs) play an important role in the
initiation and progression of hepatocellular carcinoma (HCC). Here, we identified a novel …
initiation and progression of hepatocellular carcinoma (HCC). Here, we identified a novel …