Neurotrophins are a family of proteins that regulate neuronal survival, synaptic function, and
neurotransmitter release, and elicit the plasticity and growth of axons within the adult central …

The prevalence of diabetes worldwide is at pandemic levels, with the number of patients
increasing by 5% annually. The most common complication of diabetes is peripheral …

Since its discovery, nerve growth factor (NGF) has long occupied a critical role in
developmental and adult neurobiology for its many important regulatory functions on the …

Alzheimer's disease (AD) is a progressive neurodegenerative disorder associated with
abnormal protein modification, inflammation and memory impairment. Aggregated amyloid …

Neurotrophins and their receptors modulate multiple signalling pathways to regulate
neuronal survival and to maintain axonal and dendritic networks and synaptic plasticity …

Neurotrophins (NTs) belong to a family of trophic factors that regulate the survival, growth
and programmed cell death of neurons. In mammals, there are four structurally and …

Profound and early basal forebrain cholinergic neuron (BFCN) degeneration is a hallmark of
Alzheimer's disease (AD). Loss of synapses between basal forebrain and hippocampal and …

Peripheral nerve injury disrupts the normal functions of sensory and motor neurons by
damaging the integrity of axons and Schwann cells. In contrast to the central nervous …

Besides being essential for correct development of the vertebrate nervous system the
neurotrophins also play a vital role in adult neuron survival, maintenance and regeneration …

Cell-based therapies are emerging as an alternative treatment option to promote functional
recovery in patients suffering from neurological disorders, which are the major cause of …