Preclinical and clinical studies with various stem cells, their secretomes, and extracellular
vesicles (EVs) indicate their use as a promising strategy for the treatment of various …

Brain-Derived Neurotrophic Factor (BDNF) is a dominant neurotrophic factor in the brain
which plays a crucial role in differentiation, regeneration and plasticity mechanisms. Binding …

Hypoxic preconditioning of stem cells and neural progenitor cells has been tested for
promoting cell survival after transplantation. The present investigation examined the …

The stromal stem cell fraction of many tissues and organs has demonstrated to exhibit stem
cell properties such as the capability of self-renewal and multipotency, allowing for …

Neuronal cell injury, as a consequence of acute or chronic neurological trauma, is a
significant cause of mortality around the world. On a molecular level, the condition is …

Spinal cord injury (SCI) results in loss of nervous tissue and consequently loss of motor and
sensory function. There is no treatment available that restores the injury-induced loss of …

Bone marrow stromal cells (BMSCs) have been studied as effective transplants for the
treatment of spinal cord injury (SCI). Our previous study showed that BMSCs infused into the …

The effectiveness of human bone marrow mesenchymal stem cell (hBMSC) transplantation
to treat acute and chronic liver injury has been demonstrated in animal models and in a few …

Mesenchymal stem cells (MSC) derived from bone marrow are ideal transplants for a variety
of CNS disorders and appear to support recovery after injury by secreting therapeutic …

Neurodegenerative diseases are characterized by a progressive degeneration of selective
neural populations. The lack of effective treatment and the characteristic of their pathology …