Integrative metabolomics science in Alzheimer's disease: relevance and future perspectives

S Lista, R González-Domínguez, S López-Ortiz… - Ageing Research …, 2023 - Elsevier
Alzheimer's disease (AD) is determined by various pathophysiological mechanisms starting
10–25 years before the onset of clinical symptoms. As multiple functionally interconnected …

APOE ε4 and Alzheimer's disease diagnosis associated differences in L-carnitine, GBB, TMAO, and acylcarnitines in blood and brain

CJC Huguenard, A Cseresznye, JE Evans… - Current research in …, 2023 - Elsevier
Summary Background The apolipoprotein E (APOE) ε4 allele, involved in fatty acid (FA)
metabolism, is a major genetic risk factor for Alzheimer's disease (AD). This study examined …

[图书][B] Characterization of Lipid Bioenergetic Markers in Alzheimer's Disease (AD) in Apolipoprotein E4 (APOE) and non-E4 Carriers.

CJC Huguenard - 2022 - search.proquest.com
Alzheimer's disease (AD) is a progressive neurodegenerative disease of ageing with an
estimated prevalence of 36 million worldwide. Individuals carrying one ε4 allele of the …