Definition, causes, pathogenesis, and consequences of chronic obstructive pulmonary disease exacerbations
AI Ritchie, JA Wedzicha - Clinics in chest medicine, 2020 - chestmed.theclinics.com
Acute exacerbations of chronic obstructive pulmonary disease (AECOPDs) are episodes of
symptom worsening 1 that have significant adverse consequences for patients. 2 The …
symptom worsening 1 that have significant adverse consequences for patients. 2 The …
Chronic obstructive pulmonary disease exacerbation fundamentals: diagnosis, treatment, prevention and disease impact
In chronic obstructive pulmonary disease (COPD), exacerbations (ECOPD), characterized
by an acute deterioration in respiratory symptoms, are fundamental events impacting …
by an acute deterioration in respiratory symptoms, are fundamental events impacting …
Global strategy for the diagnosis, management, and prevention of chronic obstructive lung disease 2017 report. GOLD executive summary
CF Vogelmeier, GJ Criner, FJ Martinez… - American journal of …, 2017 - atsjournals.org
This Executive Summary of the Global Strategy for the Diagnosis, Management, and
Prevention of COPD, Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2017 …
Prevention of COPD, Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2017 …
British Thoracic Society guideline on pulmonary rehabilitation in adults: accredited by NICE
Aim Pulmonary rehabilitation has established itself as a key management strategy in people
with chronic respiratory disease. The role of pulmonary rehabilitation has recently been …
with chronic respiratory disease. The role of pulmonary rehabilitation has recently been …
Long-term natural history of chronic obstructive pulmonary disease: severe exacerbations and mortality
Background The long-term natural history of chronic obstructive pulmonary disease (COPD)
in terms of successive severe exacerbations and mortality is unknown. Methods The authors …
in terms of successive severe exacerbations and mortality is unknown. Methods The authors …
Effect of roflumilast on exacerbations in patients with severe chronic obstructive pulmonary disease uncontrolled by combination therapy (REACT): a multicentre …
FJ Martinez, PMA Calverley, UM Goehring, M Brose… - The Lancet, 2015 - thelancet.com
Background Roflumilast reduces exacerbations in patients with severe chronic obstructive
pulmonary disease. Its effect in patients using fixed combinations of inhaled corticosteroids …
pulmonary disease. Its effect in patients using fixed combinations of inhaled corticosteroids …
Natural history of chronic obstructive pulmonary disease exacerbations in a general practice–based population with chronic obstructive pulmonary disease
Rationale: Acute exacerbations of chronic obstructive pulmonary disease (AECOPDs) are
important adverse events in the natural history of chronic obstructive pulmonary disease …
important adverse events in the natural history of chronic obstructive pulmonary disease …
Experimental rhinovirus infection as a human model of chronic obstructive pulmonary disease exacerbation
Rationale: Respiratory virus infections are associated with chronic obstructive pulmonary
disease (COPD) exacerbations, but a causative relationship has not been proven. Studies of …
disease (COPD) exacerbations, but a causative relationship has not been proven. Studies of …
Mechanisms and impact of the frequent exacerbator phenotype in chronic obstructive pulmonary disease
JA Wedzicha, SE Brill, JP Allinson, GC Donaldson - BMC medicine, 2013 - Springer
Exacerbations of chronic obstructive pulmonary disease (COPD) are important events that
carry significant consequences for patients. Some patients experience frequent …
carry significant consequences for patients. Some patients experience frequent …
Exacerbations of COPD
Exacerbations of chronic obstructive pulmonary disease (COPD) are defined as sustained
worsening of a patient's condition beyond normal day-to-day variations that is acute in onset …
worsening of a patient's condition beyond normal day-to-day variations that is acute in onset …