The etiology of endemic rickets was discovered a century ago. Vitamin D is the precursor of
25-hydroxyvitamin D and other metabolites, including 1, 25 (OH) 2D, the ligand for the …

Abstract Treatment of tuberculosis (TB) involves the administration of anti-mycobacterial
drugs for several months. The emergence of drug-resistant strains of Mycobacterium …

Regulation of immune function continues to be one of the most well recognized extraskeletal
actions of vitamin D. This stemmed initially from the discovery that antigen presenting cells …

Vitamin D insufficiency or deficiency (VDD) is a very prevalent condition in the general
population. Vitamin D is necessary for optimal bone mineralization, but apart from the bone …

The global impact of childhood malnutrition is staggering. The synergism between
malnutrition and infection contributes substantially to childhood morbidity and mortality …

Vitamin D deficiency, characterized by low circulating levels of calcifediol (25-
hydroxyvitamin D, 25D) has been linked to increased risk of infections of bacterial and viral …

Background A large number of observational studies have reported harmful effects of low 25-
hydroxyvitamin D (25OHD) levels on non-skeletal outcomes. We performed a systematic …

There are 9 million cases of active tuberculosis reported annually; however, an estimated
one-third of the world's population is infected with Mycobacterium tuberculosis and remains …

In addition to its role in calcium homeostasis and bone formation, a modulatory role of the
active form of vitamin D on cells of the immune system, particularly T lymphocytes, has been …

The immune system, innate and adaptive, is a highly evolved and complex network,
essential for promoting survival in an environment full of potential pathogens, while …