Fueling CARs: metabolic strategies to enhance CAR T-cell therapy
A Van der Vreken, K Vanderkerken… - … Hematology & Oncology, 2024 - Springer
CAR T cells are widely applied for relapsed hematological cancer patients. With six
approved cell therapies, for Multiple Myeloma and other B-cell malignancies, new insights …
approved cell therapies, for Multiple Myeloma and other B-cell malignancies, new insights …
[HTML][HTML] Metabolic footprint and logic through the T cell life cycle
A simple definition of life is a system that can self-replicate (proliferation) and self-sustain
(metabolism). At the cellular level, metabolism has evolved to drive proliferation, which …
(metabolism). At the cellular level, metabolism has evolved to drive proliferation, which …
[HTML][HTML] Enhanced antitumor efficacy, proliferative capacity, and alleviation of T cell exhaustion by fifth-generation chimeric antigen receptor T cells targeting B cell …
P Yuti, N Sawasdee, K Natungnuy… - Biomedicine & …, 2023 - Elsevier
Chimeric antigen receptor (CAR) T cell therapy targeting B cell maturation antigen (BCMA)
has been approved for treating multiple myeloma (MM). Some clinical studies reported …
has been approved for treating multiple myeloma (MM). Some clinical studies reported …