The incidence of heart failure (HF) continues to increase rapidly in patients with diabetes. It
is marked by myocardial remodeling, including fibrosis, hypertrophy, and cell death, leading …

Cathepsin C, an important lysosomal cysteine protease, mediates the maturation process of
neutrophil serine proteases, and participates in the inflammation and immune regulation …

Aims Neutrophil activity contributes to adverse cardiac remodelling in experimental acute
cardiac injury and is modifiable with pharmacologic agents like colchicine. Methods and …

Purpose Diabetic heart failure (DHF) or cardiomyopathy is a common complication of
diabetes; however, the underlying mechanism is not clear. In the present study, the authors …

During inflammation neutrophils become activated and segregate neutrophil serine
proteases (NSPs) to the surrounding environment in order to support a natural immune …

Diabetic cardiomyopathy (DCM) is a serious complication of diabetes, which importantly
contributes to the increased mortality of patients with diabetes. The development of DCM is …

Abstract Objectives Danzhi Jiangtang capsule (DJC) is widely used for preventing and
treating diabetic cardiomyopathy (DCM). However, the underlying mechanisms of the anti …

Inflammatory response-mediated excessive apoptosis is the main pathological alteration in
the development of diabetic cardiomyopathy (DCM). The role of astragaloside IV (AS-IV) in …

Background and objective Dilated cardiomyopathy (DCM) is a prevalent form of heart failure
results in dilation and disruption of heart. Most strikingly a majority of the DCM cases do not …

Heart structure and function change with age, and the notion that the heart may age faster
for some individuals than for others has driven interest in estimating cardiac age …