Depression is the third leading cause of disability in the world. Depressive symptoms may
be reduced within several weeks after the start of conventional antidepressants, but …

Background Inadequate pain management after surgery increases the risk of postoperative
complications and may predispose for chronic postsurgical pain. Perioperative ketamine …

Psilocybin is a naturally occurring tryptamine known for its psychedelic properties. Recent
research indicates that psilocybin may constitute a valid approach to treat depression and …

Misuse of illicit drugs is a serious problem that became the primary concern for many
authorities worldwide. Point-of-care (POC) diagnostic tools can provide accurate and fast …

Since the 2000s, an increasing number of new psychoactive substances (NPS) have
appeared on the drug market. Arylcyclohexylamine (ACH) compounds such as ketamine …

Intravenous (IV) ketamine is increasingly used off-label at subanesthetic doses for its rapid
antidepressant effect, and intranasal (IN) esketamine has been recently approved in several …

Abstract Purpose of Review Postoperative pain (POP) is among the most unpleasant
experiences that patients face after surgery. Interest in and use of N-methyl-D-aspartate …

The use of ketamine in patients with TBI has often been argued due to its possible
deleterious effects on cerebral circulation and perfusion. Early studies suggested that …

Backgrounds Ketamine is a dissociative anesthetic that is currently considered for several
new indications. Aim To deduce the safety of long-term ketamine treatment using the harm of …

Although several studies and reports have shown the potential analgesic use of
serotonergic psychedelics in cancer pain, phantom limb pain and cluster headache …