The past and the future of Langmuir and Langmuir–Blodgett films

ON Oliveira Jr, L Caseli, K Ariga - Chemical reviews, 2022 - ACS Publications
The Langmuir–Blodgett (LB) technique, through which monolayers are transferred from the
air/water interface onto a solid substrate, was the first method to allow for the controlled …

[HTML][HTML] Biophysics in cancer: The relevance of drug-membrane interaction studies

AC Alves, D Ribeiro, C Nunes, S Reis - Biochimica et Biophysica Acta (BBA …, 2016 - Elsevier
Lipidomics has been proving that membrane lipids play a crucial role in several cell
functions and are involved in several pathologies, including cancer. In fact, beyond a …

PLA/PLGA nanoparticles for sustained release of docetaxel

T Musumeci, CA Ventura, I Giannone, B Ruozi… - International journal of …, 2006 - Elsevier
This study investigates the potentiality of nanosphere colloidal suspensions as sustained
release systems for intravenous administration of docetaxel (DTX). Nanospheres were …

Getting to the bottom of Taxol biosynthesis by fungi

U Heinig, S Scholz, S Jennewein - Fungal diversity, 2013 - Springer
Taxol (paclitaxel) is a highly-oxygenated diterpenoid natural product first isolated from the
pacific yew tree (Taxus brevifolia). It is one of the most widely used anticancer drugs. Soon …

Langmuir monolayer techniques for the investigation of model bacterial membranes and antibiotic biodegradation mechanisms

M Rojewska, W Smułek, E Kaczorek, K Prochaska - Membranes, 2021 - mdpi.com
The amounts of antibiotics of anthropogenic origin released and accumulated in the
environment are known to have a negative impact on local communities of microorganisms …

Paclitaxel-clusters coated with hyaluronan as selective tumor-targeted nanovectors

I Rivkin, K Cohen, J Koffler, D Melikhov, D Peer… - Biomaterials, 2010 - Elsevier
Paclitaxel (PTX) is a widely used anti-tumor agent in the treatment of solid tumors. Lack of
selective strategies to target PTX into tumor cells together with poor solubility necessitating …

Langmuir-monolayer methodologies for characterizing protein-lipid interactions

M Elderdfi, AF Sikorski - Chemistry and physics of lipids, 2018 - Elsevier
The Langmuir-monolayer technique is a convenient method that allows for continuous
control over several membrane-specific parameters, such as molecular packing, physical …

Detailed analysis of the surface area and elasticity in the saturated 1, 2-diacylphosphatidylcholine/cholesterol binary monolayer system

T Miyoshi, S Kato - Langmuir, 2015 - ACS Publications
The surface pressure–area (π–A) isotherms of DMPC, DPPC, and DSPC/cholesterol binary
monolayers were systematically measured with great care to gain insight into the lateral …

Liposomes and other vesicular systems: structural characteristics, methods of preparation, and use in nanomedicine

E Elizondo, E Moreno, I Cabrera, A Córdoba… - Progress in molecular …, 2011 - Elsevier
Vesicular systems, especially liposomes, have generated a great deal of interest as
intelligent materials for the delivery of bioactive molecules since they can be used as …

Why are membrane targets discovered by phenotypic screens and genome sequencing in Mycobacterium tuberculosis?

RC Goldman - Tuberculosis, 2013 - Elsevier
High through put screening (HTS) was extensively used in attempts to discover new TB
drugs from libraries of pure small molecule compounds many of which complied with the …