Recent advances on modulation of H2O2 in tumor microenvironment for enhanced cancer therapeutic efficacy

Z Chu, J Yang, W Zheng, J Sun, W Wang… - Coordination Chemistry …, 2023 - Elsevier
Due to the rapid proliferation of tumors, the hydrogen peroxide (H 2 O 2) concentration of
tumor cells is higher than that of normal cells, which can be used as an effective target for …

Nano-drug delivery systems entrapping natural bioactive compounds for cancer: recent progress and future challenges

VP Chavda, AB Patel, KJ Mistry, SF Suthar… - Frontiers in …, 2022 - frontiersin.org
Cancer is a prominent cause of mortality globally, and it becomes fatal and incurable if it is
delayed in diagnosis. Chemotherapy is a type of treatment that is used to eliminate …

Engineered bacteria for enhanced radiotherapy against breast carcinoma

P Pan, X Dong, Y Chen, X Zeng, XZ Zhang - ACS nano, 2022 - ACS Publications
Radiotherapy is widely applied for multiple malignant tumors ablation in the clinic. However,
redundant doses of X-rays might destroy normal tissue in the periphery of tumor sites. Here …

Enhancing anti-tumor effect of ultrasensitive bimetallic RuCu nanoparticles as radiosensitizers with dual enzyme-like activities

B Hu, X Xiao, P Chen, J Qian, G Yuan, Y Ye, L Zeng… - Biomaterials, 2022 - Elsevier
Radiotherapy (RT), through the generation of reactive oxygen species (ROS) and DNA
damage to tumor cells caused by high-energy irradiation, has been a widely applied cancer …

New frontiers in colorectal cancer treatment combining nanotechnology with photo-and radiotherapy

SC Freitas, D Sanderson, S Caspani, R Magalhães… - Cancers, 2023 - mdpi.com
Simple Summary Although colorectal cancer is the third most common type of cancer, its
treatment strategies still have room for improvement, as current techniques carry risks that …

Albumin-modified gold nanoparticles as novel radiosensitizers for enhancing lung cancer radiotherapy

Y Chen, S Liu, Y Liao, H Yang, Z Chen… - International Journal …, 2023 - Taylor & Francis
Background Considering the strong attenuation of photons and the potential to increase the
deposition of radiation, high-atomic number nanomaterials are often used as …

Recent metal nanotheranostics for cancer diagnosis and therapy: a review

A Khorasani, D Shahbazi-Gahrouei, A Safari - Diagnostics, 2023 - mdpi.com
In recent years, there has been an increasing interest in using nanoparticles in the medical
sciences. Today, metal nanoparticles have many applications in medicine for tumor …

Application of nano‐radiosensitizers in combination cancer therapy

M Varzandeh, L Sabouri, V Mansouri… - Bioengineering & …, 2023 - Wiley Online Library
Radiosensitizers are compounds or nanostructures, which can improve the efficiency of
ionizing radiation to kill cells. Radiosensitization increases the susceptibility of cancer cells …

Nanomedicines enhance minimally invasive therapy of pancreatic cancer

P Yang, X Zhi, Y Xu, L Qian, Z Dai - Nano Today, 2023 - Elsevier
Pancreatic carcinoma (PCa) is a malignant tumor that is highly lethal and lacks an effective
treatment. Although surgical treatment, chemotherapy, and radiotherapy of PCa have …

Gold nanoparticles enhancing generation of ROS for Cs-137 radiotherapy

SW Tsai, CY Lo, SY Yu, FH Chen, HC Huang… - Nanoscale Research …, 2022 - Springer
Radiotherapy is an important modality for the treatment of cancer, eg, X-ray, Cs-137 γ-ray
(peak energy: 662 keV). An important therapy pathway of radiation is to generate the double …