Comparative analysis of gammaherpesvirus circular RNA repertoires: conserved and unique viral circular RNAs
Recent studies have identified circular RNAs (circRNAs) expressed from the Epstein-Barr
virus (EBV) and Kaposi's sarcoma herpesvirus (KSHV) human DNA tumor viruses. To gain …
virus (EBV) and Kaposi's sarcoma herpesvirus (KSHV) human DNA tumor viruses. To gain …
RNF213 modulates γ-herpesvirus infection and reactivation via targeting the viral Replication and Transcription Activator
H Tian, K Yu, L He, H Xu, C Han… - Proceedings of the …, 2023 - National Acad Sciences
Interferons (IFNs) and the products of interferon-stimulated genes (ISGs) play crucial roles in
host defense against virus infections. Although many ISGs have been characterized with …
host defense against virus infections. Although many ISGs have been characterized with …
Initiation of lytic DNA replication in Epstein–Barr virus: search for a common family mechanism
AJ Rennekamp, PM Lieberman - Future virology, 2010 - Taylor & Francis
Herpesviruses are a complex family of dsDNA viruses that are a major cause of human
disease. All family members share highly related viral replication proteins, such as DNA …
disease. All family members share highly related viral replication proteins, such as DNA …
[HTML][HTML] Direct non transcriptional role of NF-Y in DNA replication
NF-Y is a heterotrimeric transcription factor, which plays a pioneer role in the transcriptional
control of promoters containing the CCAAT-box, among which genes involved in cell cycle …
control of promoters containing the CCAAT-box, among which genes involved in cell cycle …
Multiple lytic origins of replication are required for optimal gammaherpesvirus fitness in vitro and in vivo
C Sattler, B Steer, H Adler - PLoS Pathogens, 2016 - journals.plos.org
An unresolved question in herpesvirus biology is why some herpesviruses contain more
than one lytic origin of replication (oriLyt). Using murine gammaherpesvirus 68 (MHV-68) as …
than one lytic origin of replication (oriLyt). Using murine gammaherpesvirus 68 (MHV-68) as …
Replication and transcription activator (RTA) of murine gammaherpesvirus 68 binds to an RTA-responsive element and activates the expression of ORF18
The replication and transcription activator (RTA), mainly encoded by open reading frame 50,
is an immediate-early gene product that is conserved among all characterized …
is an immediate-early gene product that is conserved among all characterized …
Murine Gammaherpesvirus 68 ORF48 Is an RTA-Responsive Gene Product and Functions in both Viral Lytic Replication and Latency during In Vivo Infection
Replication and transcription activator (RTA) of gammaherpesvirus is an immediate early
gene product and regulates the expression of many downstream viral lytic genes. ORF48 is …
gene product and regulates the expression of many downstream viral lytic genes. ORF48 is …
Cytomegalovirus Replicon-Based Regulation of Gene Expression In Vitro and In Vivo
H Mohr, CA Mohr, MR Schneider, L Scrivano… - PLoS …, 2012 - journals.plos.org
There is increasing evidence for a connection between DNA replication and the expression
of adjacent genes. Therefore, this study addressed the question of whether a herpesvirus …
of adjacent genes. Therefore, this study addressed the question of whether a herpesvirus …
CTCF and Sp1 interact with the Murine gammaherpesvirus 68 internal repeat elements
Herpesviruses maintain a dynamic balance between latency and productive infection. This
is a complex process regulated by viral and cellular factors. We have developed a Murine …
is a complex process regulated by viral and cellular factors. We have developed a Murine …
CCAAT/enhancer binding proteins play a role in oriLyt-dependent genome replication during MHV-68 de novo infection
Abstract Murine gammaherpesvirus 68 (MHV-68), a member of the gammaherpesvirus
family, replicates robustly in permissive cell lines and is able to infect laboratory mice. MHV …
family, replicates robustly in permissive cell lines and is able to infect laboratory mice. MHV …