States of oral health and disease reflect the compositional and functional capacities of, as
well as the interspecies interactions within, the oral microbiota. The oral cavity exists as a …

The ability to fight bacterial infections with antibiotics has been a longstanding cornerstone
of modern medicine. However, wide-spread overuse and misuse of antibiotics has led to …

Broad-spectrum antibiotics for suspected early-onset neonatal sepsis (sEONS) may have
pronounced effects on gut microbiome development and selection of antimicrobial …

Antibiotics are used to fight pathogens but also target commensal bacteria, disturbing the
composition of gut microbiota and causing dysbiosis and disease. Despite this well-known …

Bacteria in the gut can modulate the availability and efficacy of therapeutic drugs. However,
the systematic mapping of the interactions between drugs and bacteria has only started …

Differential abundance (DA) analysis of microbiome data continues to be a challenging
problem due to the complexity of the data. In this article we define the notion of “sampling …

Beneficial interactions between plant roots and rhizosphere microorganisms are pivotal for
plant fitness. Nevertheless, the molecular mechanisms controlling the feedback between …

Background Recent evidence suggests a role for the microbiome in pancreatic ductal
adenocarcinoma (PDAC) aetiology and progression. Objective To explore the faecal and …

Increasing evidence implicates the tumor microbiota as a factor that can influence cancer
progression. In patients with colorectal cancer (CRC), we found that pre-resection antibiotics …

Nucleotide sequence and taxonomy reference databases are critical resources for
widespread applications including marker-gene and metagenome sequencing for …