Mitochondrial damage is implicated as a major contributing factor for a number of
noncommunicable chronic diseases such as cardiovascular diseases, cancer, obesity, and …

Calcium ion (Ca2+) signaling is critical to many physiological processes, and its kinetics and
subcellular localization are tightly regulated in all cell types. All Ca2+ flux perturbations …

Mitochondrial retrograde signaling (mito-RTG) triggered by mitochondrial dysfunction plays
a potential role in regulating tumor metabolic reprogramming and cellular sensitivity to …

Mitochondria control vitally important functions in cells, including energy production, cell
signalling and regulation of cell death. Considering this, any alteration in mitochondrial …

Calcium entering mitochondria potently stimulates ATP synthesis. Increases in calcium
preserve energy synthesis in cardiomyopathies caused by mitochondrial dysfunction, and …

The therapeutic options for castration-resistant prostate cancer (CRPC) are still limited.
Natural bioactive compounds were shown to possess pro-death properties in different …

The puzzling traits related to the evolutionary aspect of mitochondria, still positions the
mitochondrion at the center of the research. The theory of endosymbiosis popularized by …

Cancer is a leading cause of death worldwide. All major tumor suppressors and oncogenes
are now recognized to have fundamental connections with metabolic pathways. A hallmark …

Perfluoroalkyl substances (PFASs) are widely used synthetic chemicals, showing
environmental/biological persistence and adverse effects on ecosystem and human health …

Abstract The plasticizer di (2-ethylhexyl) phthalate (DEHP) is frequently detected in the
environment due to the abundance of its use. These levels might be hazardous to human …