Wilms tumour (WT) is a childhood embryonal tumour that is paradigmatic of the intersection
between disrupted organogenesis and tumorigenesis. Many WT genes play a critical (non …

PURPOSE Pediatric CNS tumors are increasingly a priority, particularly with the WHO
designation of low-grade glioma (LGG) as one of six index childhood cancers. There are …

Cancer is now the second leading cause of death in the Caribbean. Despite this growing
burden, many Caribbean small island nations have health systems that struggle to provide …

Summary In 2013, the SickKids-Caribbean Initiative (SCI) was formalised among The
Hospital for Sick Children in Toronto, Canada, the University of the West Indies, and …

PURPOSE The global pediatric oncology clinical research landscape, particularly in Central
and South America, Africa, and Asia, which bear the highest burden of global childhood …

Improvements in survival for children with cancer residing in high-income countries have
been driven by the results of successive clinical trials conducted by large multi-center …

Background: Biological inflammatory status in cancer patients is evaluated with various
parameters. Limited studies have been conducted on this issue in children. Objectives: This …

Background Equitable access to essential medicines is a key facet of childhood cancer care,
recognised by WHO as vital to improved childhood cancer outcomes globally. In the …

To improve pediatric hematology and oncology outcomes, there is a recognized potential for
partnerships between low-and high-resource institutions within health care systems. The …

METHODS A narrative literature review of collaborative groups performing pediatric cancer
clinical research in each continent was conducted. An inventory of research groups was …