Acute myeloid leukemia: 2023 update on diagnosis, risk‐stratification, and management
Disease overview Acute myeloid leukemia (AML) is a frequently fatal bone marrow stem cell
cancer characterized by unbridled proliferation of malignant marrow stem cells with …
cancer characterized by unbridled proliferation of malignant marrow stem cells with …
Context-dependent functions of pattern recognition receptors in cancer
SM Man, BJ Jenkins - Nature Reviews Cancer, 2022 - nature.com
The immune system plays a critical role in shaping all facets of cancer, from the early
initiation stage through to metastatic disease and resistance to therapy. Our understanding …
initiation stage through to metastatic disease and resistance to therapy. Our understanding …
Molecular international prognostic scoring system for myelodysplastic syndromes
E Bernard, H Tuechler, PL Greenberg… - NEJM …, 2022 - evidence.nejm.org
Background Risk stratification and therapeutic decision-making for myelodysplastic
syndromes (MDS) are based on the International Prognostic Scoring System–Revised (IPSS …
syndromes (MDS) are based on the International Prognostic Scoring System–Revised (IPSS …
NCCN guidelines insights: acute myeloid leukemia, version 2.2021: featured updates to the NCCN guidelines
DA Pollyea, D Bixby, A Perl, VR Bhatt… - Journal of the National …, 2021 - jnccn.org
The NCCN Guidelines for Acute Myeloid Leukemia (AML) provide recommendations for the
diagnosis and treatment of adults with AML based on clinical trials that have led to …
diagnosis and treatment of adults with AML based on clinical trials that have led to …
Diagnosis and management of AML in adults: 2017 ELN recommendations from an international expert panel
H Döhner, E Estey, D Grimwade… - Blood, The Journal …, 2017 - ashpublications.org
The first edition of the European LeukemiaNet (ELN) recommendations for diagnosis and
management of acute myeloid leukemia (AML) in adults, published in 2010, has found …
management of acute myeloid leukemia (AML) in adults, published in 2010, has found …
RNA splicing factors as oncoproteins and tumour suppressors
H Dvinge, E Kim, O Abdel-Wahab… - Nature Reviews Cancer, 2016 - nature.com
The recent genomic characterization of cancers has revealed recurrent somatic point
mutations and copy number changes affecting genes encoding RNA splicing factors. Initial …
mutations and copy number changes affecting genes encoding RNA splicing factors. Initial …
The genetics of myelodysplastic syndrome: from clonal haematopoiesis to secondary leukaemia
AS Sperling, CJ Gibson, BL Ebert - Nature Reviews Cancer, 2017 - nature.com
Myelodysplastic syndrome (MDS) is a clonal disease that arises from the expansion of
mutated haematopoietic stem cells. In a spectrum of myeloid disorders ranging from clonal …
mutated haematopoietic stem cells. In a spectrum of myeloid disorders ranging from clonal …
Donor clonal hematopoiesis and recipient outcomes after transplantation
CJ Gibson, HT Kim, L Zhao, HM Murdock… - Journal of Clinical …, 2022 - ascopubs.org
PURPOSE Clonal hematopoiesis (CH) can be transmitted from a donor to a recipient during
allogeneic hematopoietic cell transplantation. Exclusion of candidate donors with CH is …
allogeneic hematopoietic cell transplantation. Exclusion of candidate donors with CH is …
Germ line DDX41 mutations define a unique subtype of myeloid neoplasms
Germ line DDX41 variants have been implicated in late-onset myeloid neoplasms (MNs).
Despite an increasing number of publications, many important features of DDX41-mutated …
Despite an increasing number of publications, many important features of DDX41-mutated …
Acute myeloid leukemia
H Döhner, DJ Weisdorf… - New England Journal of …, 2015 - Mass Medical Soc
Acute Myeloid Leukemia | New England Journal of Medicine Skip to main content The New
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