[HTML][HTML] The association between antidiabetic agents and clinical outcomes of COVID-19 patients with diabetes: a Bayesian network meta-analysis

Y Chen, X Lv, S Lin, M Arshad, M Dai - Frontiers in Endocrinology, 2022 - frontiersin.org
Aims This study aimed to assess the impact of different antidiabetic agents on individuals
with diabetes and COVID-19. Methods We searched PubMed, Web of Science, Embase …

[HTML][HTML] Risk phenotypes of diabetes and association with COVID-19 severity and death: an update of a living systematic review and meta-analysis

S Schlesinger, A Lang, N Christodoulou, P Linnerz… - Diabetologia, 2023 - Springer
Aims/hypothesis To provide a systematic overview of the current body of evidence on high-
risk phenotypes of diabetes associated with COVID-19 severity and death. Methods This is …

Preadmission use of antidiabetic medications and mortality among patients with COVID-19 having type 2 diabetes: A meta-analysis

NN Nguyen, DS Ho, HS Nguyen, DKN Ho, HY Li… - Metabolism, 2022 - Elsevier
Background Diabetes is an independent predictor of poor outcomes in patients with COVID-
19. We compared the effects of the preadmission use of antidiabetic medications on the in …

Metformin in SARS-CoV-2 infection: A hidden path–from altered inflammation to reduced mortality. A review from the literature

AR Pedrosa, DC Martins, M Rizzo… - Journal of Diabetes and its …, 2023 - Elsevier
SARS-CoV-2 infection has been a major threat to human health and a huge challenge to
Medicine. In only two years, COVID-19 affected> 350 million people, causing> 5.6 million …

[HTML][HTML] Targeting T cell (oxidative) metabolism to improve immunity to viral infection in the context of obesity

E Greene, NJ MacIver - Frontiers in Immunology, 2022 - frontiersin.org
Disorders of systemic metabolism can influence immunity. Individuals with obesity are
known to have increased inflammation, increased risk to select autoimmune diseases …

[HTML][HTML] Metformin is a potential therapeutic for COVID-19/LUAD by regulating glucose metabolism

Y Hou, Z Yang, B Xiang, J Liu, L Geng, D Xu, M Zhan… - Scientific Reports, 2024 - nature.com
Lung adenocarcinoma (LUAD) is the most common and aggressive subtype of lung cancer,
and coronavirus disease 2019 (COVID-19) has become a serious public health threat …

Metformin use associated with lower rate of hospitalization for influenza in individuals with diabetes

E Greene, CL Green, J Hurst… - Diabetes, Obesity and …, 2024 - Wiley Online Library
Aim To investigate if patients with diabetes taking metformin have better outcomes versus
those not taking metformin following an emergency room visit for influenza. Methods Using …

Metformin as a therapeutic agent for obesity-associated immune dysfunction

D Rajeev, NJ MacIver - The Journal of Nutrition, 2024 - Elsevier
Obesity is associated with impaired immune function, characterized by inflammation, and
leading to poor response to infection, impaired vaccine response, increased susceptibility to …

The Effect of Antihyperglycemic Medications on COVID-19: A Meta-analysis and Systematic Review from Observational Studies

ZH Song, QM Huang, SS Xu, JB Zhou… - Therapeutic Innovation & …, 2024 - Springer
Background Diabetes, a chronic disease worldwide, may be associated with a poorer
prognosis in patients with coronavirus disease 2019 (COVID-19). While some …

[HTML][HTML] Metformin in COVID-19: Is There a Role Beyond Glycemic Control?

L Nagendra, S Bhattacharya, S Kalra… - International Journal of …, 2023 - ncbi.nlm.nih.gov
Results Several overlapping mechanisms have been proposed to explain its antiviral
properties. It could bring about conformational changes in the angiotensin-converting …