[HTML][HTML] lncRNA NEAT1: Key player in neurodegenerative diseases

K Li, Z Wang - Ageing Research Reviews, 2023 - Elsevier
Neurodegenerative diseases are the most common causes of disability worldwide. Given
their high prevalence, devastating symptoms, and lack of definitive diagnostic tests, there is …

Role of dopamine in the pathophysiology of Parkinson's disease

ZD Zhou, LX Yi, DQ Wang, TM Lim, EK Tan - Translational …, 2023 - Springer
A pathological feature of Parkinson's disease (PD) is the progressive loss of dopaminergic
neurons and decreased dopamine (DA) content in the substantia nigra pars compacta in PD …

Efficacy of repetitive transcranial magnetic stimulation in Parkinson's disease: a systematic review and meta-analysis of randomised controlled trials

W Zhang, B Deng, F Xie, H Zhou, JF Guo, H Jiang… - …, 2022 - thelancet.com
Background Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive form of
brain stimulation that positively regulates the motor and non-motor symptoms of Parkinson's …

The role of tyrosine hydroxylase–dopamine pathway in Parkinson's disease pathogenesis

ZD Zhou, WT Saw, PGH Ho, ZW Zhang, L Zeng… - Cellular and Molecular …, 2022 - Springer
Background Parkinson's disease (PD) is characterized by selective and progressive
dopamine (DA) neuron loss in the substantia nigra and other brain regions, with the …

The Effects of Andrographis paniculata (Burm.F.) Wall. Ex Nees and Andrographolide on Neuroinflammation in the Treatment of Neurodegenerative Diseases

F Bosco, S Ruga, R Citraro, A Leo, L Guarnieri… - Nutrients, 2023 - mdpi.com
Neurodegenerative diseases (NDs) affect millions of people worldwide, and to date,
Alzheimer's and Parkinson's diseases are the most common NDs. Of the many risk factors …

Potential therapeutic effects and pharmacological evidence of sinomenine in central nervous system disorders

H Hong, X Lu, Q Lu, C Huang, Z Cui - Frontiers in Pharmacology, 2022 - frontiersin.org
Sinomenine is a natural compound extracted from the medicinal plant Sinomenium acutum.
Its supplementation has been shown to present benefits in a variety of animal models of …

Modified SqueezeNet architecture for Parkinson's disease detection based on keypress data

LS Bernardo, R Damaševičius, SH Ling… - biomedicines, 2022 - mdpi.com
Parkinson's disease (PD) is the most common form of Parkinsonism, which is a group of
neurological disorders with PD-like motor impairments. The disease affects over 6 million …

Stem cells: innovative therapeutic options for neurodegenerative diseases?

G Bonaventura, A Munafò, CM Bellanca, V La Cognata… - Cells, 2021 - mdpi.com
Neurodegenerative diseases are characterized by the progressive loss of structure and/or
function of both neurons and glial cells, leading to different degrees of pathology and loss of …

Roles of transcription factors in the development and reprogramming of the dopaminergic neurons

L Tian, M Al-Nusaif, X Chen, S Li, W Le - International Journal of …, 2022 - mdpi.com
The meso-diencephalic dopaminergic (mdDA) neurons regulate various critical processes in
the mammalian nervous system, including voluntary movement and a wide range of …

The role of the microbiota-gut-brain axis and intestinal microbiome dysregulation in Parkinson's disease

Q Li, L Meng, L Chen, X Shi, L Tu, Q Zhou, J Yu… - Frontiers in …, 2023 - frontiersin.org
Parkinson's disease (PD) is a complex progressive neurodegenerative disease associated
with aging. Its main pathological feature is the degeneration and loss of dopaminergic …