The kinesin, dynein, and myosin superfamily molecular motors have fundamental roles in
neuronal function, plasticity, morphogenesis, and survival by transporting cargos such as …

Tau protein is abundant in the central nervous system and involved in microtubule assembly
and stabilization. It is predominantly associated with axonal microtubules and present at …

▪ Abstract Trk receptors are a family of three receptor tyrosine kinases, each of which can be
activated by one or more of four neurotrophins—nerve growth factor (NGF), brain-derived …

Neurons have extensive processes and communication between those processes and the
cell body is crucial to neuronal function and survival. Thus, neurons are uniquely dependent …

Target-derived NGF promotes the phenotypic maintenance of mature dorsal root ganglion
(DRG) nociceptive neurons. Here, we provide in vivo and in vitro evidence for the presence …

We show that the BMP ortholog Gbb can signal by a retrograde mechanism to regulate
synapse growth of the Drosophila neuromuscular junction (NMJ). gbb mutants have a …

Cytoplasmic dynein has long been thought to be responsible for retrograde axonal transport.
As the number of cellular roles for this multifunctional protein has expanded, the complexity …

Neuronal connections are established and refined through a series of developmental
programs that involve axon and dendrite specification, process growth, target innervation …

Brain‐derived neurotrophic factor (BDNF) and its receptors TrkB and p75 regulate dendritic
and axonal growth during development and maintenance of the mature nervous system; …

Target-derived neurotrophins are required for the growth and survival of innervating
neurons. When released by postsynaptic targets, neurotrophins bind receptors (Trks) on …