MicroRNA: dynamic regulators of macrophage polarization and plasticity

JB Self-Fordham, AR Naqvi, JR Uttamani… - Frontiers in …, 2017 - frontiersin.org
The ability of a healthy immune system to clear the plethora of antigens it encounters
incessantly relies on the enormous plasticity displayed by the comprising cell types …

Different modalities of host cell death and their impact on Mycobacterium tuberculosis infection

A Nisa, FC Kipper, D Panigrahy… - … of Physiology-Cell …, 2022 - journals.physiology.org
Mycobacterium tuberculosis (Mtb) is the pathogen that causes tuberculosis (TB), a leading
infectious disease of humans worldwide. One of the main histopathological hallmarks of TB …

Inducible degradation of lncRNA Sros1 promotes IFN-γ-mediated activation of innate immune responses by stabilizing Stat1 mRNA

H Xu, Y Jiang, X Xu, X Su, Y Liu, Y Ma, Y Zhao… - Nature …, 2019 - nature.com
Abstract Interferon-γ (IFN-γ) is essential for the innate immune response to intracellular
bacteria. Noncoding RNAs and RNA-binding proteins (RBPs) need to be further considered …

[HTML][HTML] MicroRNAs in the interaction between host and bacterial pathogens

C Maudet, M Mano, A Eulalio - FEBS letters, 2014 - Elsevier
MicroRNAs (miRNAs) are small non-coding RNAs with a central role in the post-
transcriptional control of gene expression, that have been implicated in a wide-range of …

Identification of antigens presented by MHC for vaccines against tuberculosis

P Bettencourt, J Müller, A Nicastri, D Cantillon… - npj Vaccines, 2020 - nature.com
Mycobacterium tuberculosis (M. tb) is responsible for more deaths globally than any other
pathogen. The only available vaccine, bacillus Calmette-Guérin (BCG), has variable efficacy …

Exosomal ncRNAs profiling of mycobacterial infection identified miRNA-185-5p as a novel biomarker for tuberculosis

AC Kaushik, Q Wu, L Lin, H Li, L Zhao… - Briefings in …, 2021 - academic.oup.com
Background: There are ever increasing researches implying that noncoded RNAs (ncRNAs)
specifically circular RNAs (circRNAs) and microRNAs (miRNAs) in exosomes play vital roles …

The Role of microRNAs and Long Non-Coding RNAs in the Regulation of the Immune Response to Mycobacterium tuberculosis Infection

M Kundu, J Basu - Frontiers in immunology, 2021 - frontiersin.org
Non-coding RNAs have emerged as critical regulators of the immune response to infection.
MicroRNAs (miRNAs) are small non-coding RNAs which regulate host defense mechanisms …

MicroRNAs at the host–bacteria interface: host defense or bacterial offense

C Aguilar, M Mano, A Eulalio - Trends in microbiology, 2019 - cell.com
MicroRNAs are a class of small noncoding RNAs that act as major post-transcriptional
regulators of gene expression. They are currently recognized for their important role in the …

miRNAs in tuberculosis: new avenues for diagnosis and host-directed therapy

N Sabir, T Hussain, SZA Shah, A Peramo… - Frontiers in …, 2018 - frontiersin.org
Tuberculosis (TB) is one of the most fatal infectious diseases and a leading cause of
mortality, with 95% of these deaths occurring in developing countries. The causative agent …

Small RNA profiles of serum exosomes derived from individuals with latent and active tuberculosis

L Lyu, X Zhang, C Li, T Yang, J Wang, L Pan… - Frontiers in …, 2019 - frontiersin.org
Tuberculosis (TB) has been the leading lethal infectious disease worldwide since 2014, and
about one third of the world's population has a latent TB infection (LTBI). This is largely …