The effects of air pollution on the brain: a review of studies interfacing environmental epidemiology and neuroimaging

P de Prado Bert, EMH Mercader, J Pujol… - Current environmental …, 2018 - Springer
Abstract Purpose of Review An emerging body of evidence has raised concern regarding
the potentially harmful effects of inhaled pollutants on the central nervous system during the …

Biomarkers of manganese intoxication

W Zheng, SX Fu, U Dydak, DM Cowan - Neurotoxicology, 2011 - Elsevier
Manganese (Mn), upon absorption, is primarily sequestered in tissue and intracellular
compartments. For this reason, blood Mn concentration does not always accurately reflect …

Basal ganglia intensity indices and diffusion weighted imaging in manganese-exposed welders

SR Criswell, JS Perlmutter, JL Huang… - Occupational and …, 2012 - oem.bmj.com
Objectives Manganese exposure leads to diffuse cerebral metal deposition with the highest
concentration in the globus pallidus associated with increased T1-weighted MRI signal. T1 …

Blood manganese as an exposure biomarker: state of the evidence

MG Baker, CD Simpson, B Stover… - … of occupational and …, 2014 - Taylor & Francis
Despite evidence of adverse health effects resulting from exposure to manganese (Mn),
biomarkers of exposure are poorly understood. To enhance understanding, mean blood Mn …

Environmental exposure to manganese in air: Associations with cognitive functions

RM Bowler, ES Kornblith, VV Gocheva, MA Colledge… - Neurotoxicology, 2015 - Elsevier
Manganese (Mn), an essential element, can be neurotoxic in high doses. This cross-
sectional study explored the cognitive function of adults residing in two towns (Marietta and …

[HTML][HTML] Whole-brain mapping of increased manganese levels in welders and its association with exposure and motor function

H Monsivais, CL Yeh, A Edmondson, R Harold… - NeuroImage, 2024 - Elsevier
Although manganese (Mn) is a trace metal essential for humans, chronic exposure to Mn
can cause accumulation of this metal ion in the brain leading to an increased risk of …

[HTML][HTML] Neurological outcomes associated with low-level manganese exposure in an inception cohort of asymptomatic welding trainees

MG Baker, SR Criswell, BA Racette… - … journal of work …, 2015 - ncbi.nlm.nih.gov
Objective Long-term, high-level exposure to manganese (Mn) is associated with impaired
central nervous system (CNS) function. We quantitatively explored relations between low …

Manganese accumulation in the olfactory bulbs and other brain regions of “asymptomatic” welders

S Sen, MR Flynn, G Du, AI Tröster, H An… - Toxicological …, 2011 - academic.oup.com
Welding-generated metallic fumes contain a substantial amount of manganese (Mn), making
welders susceptible to Mn toxicity. Although overt Mn toxicity manifests as a type of …

Derivation of an occupational exposure level for manganese in welding fumes

LA Bailey, LE Kerper, JE Goodman - Neurotoxicology, 2018 - Elsevier
Exposure to high levels of manganese (Mn) in occupational settings is known to lead to
adverse neurological effects. Since Mn is an essential nutrient, there are mechanisms that …

The application of PBPK models in estimating human brain tissue manganese concentrations

SP Ramoju, DR Mattison, B Milton, D McGough… - Neurotoxicology, 2017 - Elsevier
Mn is an essential element that causes neurotoxicity in humans when inhaled at high
concentrations. This metal has well-recognized route-dependent differences in absorption …