Adult neurogenesis, the process by which neurons are generated in certain areas of the
adult brain, declines in an age-dependent manner and is one potential target for extending …

Many behavioral experiences are known to promote hippocampal neurogenesis. In contrast,
the ability of behavioral experiences to influence the production of oligodendrocytes and …

Aging is a multifactorial process associated with an increased susceptibility to
neurodegenerative disorders which can be related to chronic inflammation. Chronic …

Recent biochemical and behavioural evidence indicates that metabolic hormones not only
regulate energy intake and nutrient content, but also modulate plasticity and cognition in the …

Aging, a complex process associated with various structural, functional and metabolic
changes in the brain, is an important risk factor for neurodegenerative diseases and stroke …

Aging is a significant risk factor for cognitive decline associated with neurodegenerative
diseases, which makes understanding what promotes 'healthy brain aging'very important …

Background Brain aging is a multi-factorial process due to both genetic and environmental
factors. The zebrafish has recently become a popular model organism for examining aging …

Huntington's disease (HD) is a neurodegenerative disorder caused by a CAG repeat
expansion in the first exon of the gene huntingtin. There is no treatment to prevent or delay …

It is widely known that caloric restriction (CR) has benefits on several organic systems,
including the central nervous system. However, the majority of the CR studies was …

Dietary restriction (DR; sometimes called calorie restriction) has profound beneficial effects
on physiological, psychological, and behavioral outcomes in animals and in humans. We …