MALDI-TOF mass spectrometry: an emerging technology for microbial identification and diagnosis

N Singhal, M Kumar, PK Kanaujia, JS Virdi - Frontiers in microbiology, 2015 - frontiersin.org
Currently microorganisms are best identified using 16S rRNA and 18S rRNA gene
sequencing. However, in recent years matrix assisted laser desorption ionization-time of …

Detecting biothreat agents: From current diagnostics to developing sensor technologies

SA Walper, G Lasarte Aragonés, KE Sapsford… - ACS …, 2018 - ACS Publications
Although a fundamental understanding of the pathogenicity of most biothreat agents has
been elucidated and available treatments have increased substantially over the past …

Magnetic quantum dot based lateral flow assay biosensor for multiplex and sensitive detection of protein toxins in food samples

C Wang, R Xiao, S Wang, X Yang, Z Bai, X Li… - Biosensors and …, 2019 - Elsevier
Protein toxins, such as botulinum neurotoxin type A (BoNT/A) and staphylococcal
enterotoxin B (SEB), easily pollute food and water and are ultra-toxic to humans and …

Applications of MALDI-MS/MS-based proteomics in biomedical research

L Darie-Ion, D Whitham, M Jayathirtha, Y Rai… - Molecules, 2022 - mdpi.com
Matrix-assisted laser desorption/ionization (MALDI) mass spectrometry (MS) is one of the
most widely used techniques in proteomics to achieve structural identification and …

Foodborne pathogens and their toxins

T Martinović, U Andjelković, MŠ Gajdošik, D Rešetar… - Journal of …, 2016 - Elsevier
Foodborne pathogens, mostly bacteria and fungi, but also some viruses, prions and
protozoa, contaminate food during production and processing, but also during storage and …

An update on the routine application of MALDI-TOF MS in clinical microbiology

M Welker, A Van Belkum, V Girard… - Expert review of …, 2019 - Taylor & Francis
Introduction: Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry
(MALDI-TOF MS) has entered clinical diagnostics and is today a generally accepted and …

What are we imaging? Software tools and experimental strategies for annotation and identification of small molecules in mass spectrometry imaging

G Baquer, L Sementé, T Mahamdi… - Mass Spectrometry …, 2023 - Wiley Online Library
Mass spectrometry imaging (MSI) has become a widespread analytical technique to perform
nonlabeled spatial molecular identification. The Achilles' heel of MSI is the annotation and …

Detection of toxins involved in foodborne diseases caused by Gram‐positive bacteria

A Rajkovic, J Jovanovic, S Monteiro… - … reviews in food …, 2020 - Wiley Online Library
Bacterial toxins are food safety hazards causing about 10% of all reported foodborne
outbreaks in Europe. Pertinent to Gram‐positive pathogens, the most relevant toxins are …

Proteome-based bacterial identification using matrix-assisted laser desorption ionization–time of flight mass spectrometry (MALDI-TOF MS): A revolutionary shift in …

F Nomura - Biochimica et Biophysica Acta (BBA)-Proteins and …, 2015 - Elsevier
Rapid and accurate identification of microorganisms, a prerequisite for appropriate patient
care and infection control, is a critical function of any clinical microbiology laboratory. Matrix …

MALDI-TOF mass spectrometry technology as a tool for the rapid diagnosis of antimicrobial resistance in bacteria

EJ Yoon, SH Jeong - Antibiotics, 2021 - mdpi.com
Species identification by using matrix-assisted laser desorption/ionization time-of-flight mass
spectrometry (MALDI-TOF MS) is a routine diagnostic process for infectious diseases in …