Quinolines, a perpetual, multipurpose scaffold in medicinal chemistry
Quinoline is a versatile pharmacophore, a privileged scaffold and an outstanding fused
heterocyclic compound with a wide range of pharmacological prospective such as …
heterocyclic compound with a wide range of pharmacological prospective such as …
Pyrazoline hybrids as promising anticancer agents: An up-to-date overview
D Matiadis, M Sagnou - International Journal of Molecular Sciences, 2020 - mdpi.com
Pyrazolines are five-membered heterocycles possessing two adjacent nitrogens. They have
attracted significant attention from organic and medicinal chemists due to their potent …
attracted significant attention from organic and medicinal chemists due to their potent …
New mixed‐ligand thioether‐quinoline complexes of nickel (II), cobalt (II), and copper (II): Synthesis, structural elucidation, density functional theory, antimicrobial …
HM Abd El‐Lateef, MM Khalaf… - Applied …, 2023 - Wiley Online Library
The main purpose of the current work is the design and synthesis of new Co (II), Ni (II), and
Cu (II) mixed‐ligand complexes derived from simple and easily synthesized azo‐ligand,[2 …
Cu (II) mixed‐ligand complexes derived from simple and easily synthesized azo‐ligand,[2 …
Synthesis, biological evaluation and molecular docking of novel pyrazole derivatives as potent carbonic anhydrase and acetylcholinesterase inhibitors
A series of substituted pyrazole compounds (1–8 and 9a, b) were synthesized and their
structure was characterized by IR, NMR, and Mass analysis. These obtained novel pyrazole …
structure was characterized by IR, NMR, and Mass analysis. These obtained novel pyrazole …
[HTML][HTML] A comprehensive review on pyrazoline based heterocyclic hybrids as potent anticancer agents
Cancer is one of the leading causes of death globally, around 10 million deaths are reported
every year due to cancer. Some clinically approved anticancer drugs play a riveting role in …
every year due to cancer. Some clinically approved anticancer drugs play a riveting role in …
Chalcone hybrids as potential anticancer agents: Current development, mechanism of action, and structure‐activity relationship
F Gao, G Huang, J Xiao - Medicinal research reviews, 2020 - Wiley Online Library
The continuous emergency of drug‐resistant cancers and the low specificity of anticancer
agents have been the major challenges in the control and treatment of cancer, making an …
agents have been the major challenges in the control and treatment of cancer, making an …
Antimicrobial, antioxidant, and anticancer activities of some novel isoxazole ring containing chalcone and dihydropyrazole derivatives
Our previous work identified isoxazole-based chalcones and their dihydropyrazole
derivatives as two important five-membered heterocycles having antitubercular activity …
derivatives as two important five-membered heterocycles having antitubercular activity …
A comprehensive overview of the medicinal chemistry of antifungal drugs: perspectives and promise
The emergence of new fungal pathogens makes the development of new antifungal drugs a
medical imperative that in recent years motivates the talents of numerous investigators …
medical imperative that in recent years motivates the talents of numerous investigators …
Quinolines and quinolones as antibacterial, antifungal, anti-virulence, antiviral and anti-parasitic agents
Infective diseases have become health threat of a global proportion due to appearance and
spread of microorganisms resistant to majority of therapeutics currently used for their …
spread of microorganisms resistant to majority of therapeutics currently used for their …
The status of cryptococcosis in Latin America
C Firacative, J Lizarazo, MT Illnait-Zaragozí… - Memórias do Instituto …, 2018 - SciELO Brasil
Cryptococcosis is a life-threatening fungal infection caused by the encapsulated yeasts
Cryptococcus neoformans and C. gattii, acquired from the environment. In Latin America, as …
Cryptococcus neoformans and C. gattii, acquired from the environment. In Latin America, as …