[PDF][PDF] Hypersensitivity reactions to β-lactams: relevance of hapten-protein conjugates.

A Ariza, C Mayorga, TD Fernandez, N Barbero… - 2015 - repositoriosalud.es
β-Lactams (BL) are the drugs most frequently involved in allergic reactions. They are
classified according to their chemical structure as penicillins, cephalosporins, monobactams …

[PDF][PDF] In Vitro Diagnostic Testing for Antibiotic Allergy

I Doña, MJ Torres, MI Montañez… - Allergy, asthma & …, 2017 - synapse.koreamed.org
Allergy to antibiotics is an important worldwide problem, with an estimated prevalence of up
to 10% of the population. Reaction patterns for different antibiotics have changed in …

Mesoporous silica nanoparticles decorated with polycationic dendrimers for infection treatment

B Gonzalez, M Colilla, J Diez, D Pedraza, M Guembe… - Acta biomaterialia, 2018 - Elsevier
This work aims to provide an effective and novel solution for the treatment of infection by
using nanovehicles loaded with antibiotics capable of penetrating the bacterial wall, thus …

Highly sensitive dendrimer-based nanoplasmonic biosensor for drug allergy diagnosis

M Soler, P Mesa-Antunez, MC Estevez… - Biosensors and …, 2015 - Elsevier
A label-free biosensing strategy for amoxicillin (AX) allergy diagnosis based on the
combination of novel dendrimer-based conjugates and a recently developed …

Mesoporous Silica Nanoparticles Decorated with Carbosilane Dendrons as New Non‐viral Oligonucleotide Delivery Carriers

Á Martínez, E Fuentes‐Paniagua… - … A European Journal, 2015 - Wiley Online Library
A novel nanosystem based on mesoporous silica nanoparticles covered with carbosilane
dendrons grafted on the external surface of the nanoparticles is reported. This system is able …

Evolution of diagnostic approaches in betalactam hypersensitivity

TD Fernandez, C Mayorga, M Salas… - Expert review of …, 2017 - Taylor & Francis
Introduction: Betalactams are the most widely used drugs against infections and the primary
cause of antibiotic hypersensitivity reactions. Reaction patterns for different betalactams …

Electrochemical immunosensor for detection of prostate specific antigen based on CNSs/Thi@ AuNPs nanocomposites as sensing platform

L Li, S Zhang, L Yu, W Zhang, Y Wei, D Feng - International Journal of …, 2022 - Elsevier
A sensitive immunosensor for quantifying prostate specific antigen (PSA) had been
described. In the design, gold nanoparticles decorated thionine-functionalized carbon …

A sensitive fluorescent immunoassay for prostate specific antigen detection based on signal amplify strategy of horseradish peroxidase and silicon dioxide …

L Li, W Zhang, Y Wei, L Yu… - Journal of Analytical …, 2022 - Wiley Online Library
A simple, sensitive, and fluorescent immunoassay for the detection of prostate‐specific
antigen (PSA) based on horseradish peroxidase and silicon dioxide nanospheres as a …

Multiepitope dendrimeric antigen-silica particle composites as nano-based platforms for specific recognition of IgEs

V Gil-Ocaña, IM Jimenez, C Mayorga, I Doña… - Frontiers in …, 2021 - frontiersin.org
β-lactam antibiotics (BLs) are the drugs most frequently involved in drug hypersensitivity
reactions. However, current in vitro diagnostic tests have limited sensitivity, partly due to a …

Dendrimeric antigens for drug allergy diagnosis: a new approach for basophil activation tests

N Molina, A Martin-Serrano, TD Fernandez, A Tesfaye… - Molecules, 2018 - mdpi.com
Dendrimeric Antigens (DeAns) consist of dendrimers decorated with multiple units of drug
antigenic determinants. These conjugates have been shown to be a powerful tool for …