Signaling pathways in obesity: mechanisms and therapeutic interventions
X Wen, B Zhang, B Wu, H Xiao, Z Li, R Li… - Signal transduction and …, 2022 - nature.com
Obesity is a complex, chronic disease and global public health challenge. Characterized by
excessive fat accumulation in the body, obesity sharply increases the risk of several …
excessive fat accumulation in the body, obesity sharply increases the risk of several …
[HTML][HTML] Pharmacology of human trace amine-associated receptors: Therapeutic opportunities and challenges
The discovery in 2001 of a G protein-coupled receptor family, subsequently termed trace
amine-associated receptors (TAAR), triggered a resurgence of interest in so-called trace …
amine-associated receptors (TAAR), triggered a resurgence of interest in so-called trace …
Shock–classification and pathophysiological principles of therapeutics
ON Kislitsina, JD Rich, JE Wilcox… - Current cardiology …, 2019 - ingentaconnect.com
The management of patients with shock is extremely challenging because of the myriad of
possible clinical presentations in cardiogenic shock, septic shock and hypovolemic shock …
possible clinical presentations in cardiogenic shock, septic shock and hypovolemic shock …
The trace amine-associated receptor 1 agonist RO5256390 blocks compulsive, binge-like eating in rats
A Ferragud, AD Howell, CF Moore, TL Ta… - …, 2017 - nature.com
Compulsive, binge eating of highly palatable food constitutes a core feature of some forms of
obesity and eating disorders, as well as of the recently proposed disorder of food addiction …
obesity and eating disorders, as well as of the recently proposed disorder of food addiction …
The biology of addiction
B MacNicol - Canadian Journal of Anesthesia/Journal canadien d' …, 2017 - Springer
In this narrative review, the neurobiological mechanisms underlying substance abuse and
addiction are discussed with a particular emphasis on the mechanisms that promote …
addiction are discussed with a particular emphasis on the mechanisms that promote …
Role of neurochemicals in the interaction between the microbiota and the immune and the nervous system of the host organism
AV Oleskin, BA Shenderov, VS Rogovsky - Probiotics and Antimicrobial …, 2017 - Springer
This work is concerned with the role of evolutionary conserved substances,
neurotransmitters, and neurohormones, within the complex framework of the microbial …
neurotransmitters, and neurohormones, within the complex framework of the microbial …
Thyronamines and derivatives: physiological relevance, pharmacological actions, and future research directions
CS Hoefig, R Zucchi, J Köhrle - Thyroid, 2016 - liebertpub.com
Thyronamines (3-T1AM, T0AM) are endogenous compounds probably derived from L-
thyroxine or its intermediate metabolites. Combined activities of intestinal deiodinases and …
thyroxine or its intermediate metabolites. Combined activities of intestinal deiodinases and …
Actions of trace amines in the brain-gut-microbiome axis via trace amine-associated receptor-1 (TAAR1)
K Bugda Gwilt, DP González, N Olliffe, H Oller… - Cellular and molecular …, 2020 - Springer
Trace amines and their primary receptor, Trace Amine-Associated Receptor-1 (TAAR1) are
widely studied for their involvement in the pathogenesis of neuropsychiatric disorders …
widely studied for their involvement in the pathogenesis of neuropsychiatric disorders …
Role of trace amine-associated receptor 1 in nicotine's behavioral and neurochemical effects
Nicotine addiction and abuse remains a global health issue. To date, the fundamental
neurobiological mechanism of nicotine addiction remains incompletely understood. Trace …
neurobiological mechanism of nicotine addiction remains incompletely understood. Trace …
Molecular neurological correlates of endorphinergic/dopaminergic mechanisms in reward circuitry linked to endorphinergic deficiency syndrome (EDS)
The consensus of the current literature strongly supports the concept that brain
neurotransmitters, and second messengers involved in the net release of dopamine in the …
neurotransmitters, and second messengers involved in the net release of dopamine in the …