Early growth response‐1, an integrative sensor in cardiovascular and inflammatory disease

LM Khachigian - Journal of the American Heart Association, 2021 - Am Heart Assoc
Early growth response‐1 (Egr‐1) is a master regulator and transcriptional sensor in vascular
dysfunction and disease. This article reviews recent developments in our understanding of …

[HTML][HTML] Chicoric acid prevents PDGF-BB-induced VSMC dedifferentiation, proliferation and migration by suppressing ROS/NFκB/mTOR/P70S6K signaling cascade

QB Lu, MY Wan, PY Wang, CX Zhang, DY Xu, X Liao… - Redox biology, 2018 - Elsevier
Phenotypic switch of vascular smooth muscle cells (VSMCs) is characterized by increased
expressions of VSMC synthetic markers and decreased levels of VSMC contractile markers …

Notch signaling in endothelial cells: is it the therapeutic target for vascular neointimal hyperplasia?

DY Tian, XR Jin, X Zeng, Y Wang - International journal of molecular …, 2017 - mdpi.com
Blood vessels respond to injury through a healing process that includes neointimal
hyperplasia. The vascular endothelium is a monolayer of cells that separates the outer …

Impact of smoking on cardiovascular risk and premature ageing: Findings from the STANISLAS cohort

T Rastogi, N Girerd, Z Lamiral, E Bresso, E Bozec… - Atherosclerosis, 2022 - Elsevier
Background and aims Smoking may lead to premature ageing, but the impact on the
cardiovascular system and circulating proteins needs further investigation. In the present …

Early growth response 1 exacerbates thoracic aortic aneurysm and dissection of mice by inducing the phenotypic switching of vascular smooth muscle cell through the …

X Han, S Xu, K Hu, Y Yu, X Wang, C Qu… - Acta …, 2024 - Wiley Online Library
Aim Vascular smooth muscle cell (VSMC) phenotypic switching has been reported to
regulate vascular function and thoracic aortic aneurysm and dissection (TAAD) progression …

Promoter usage and dynamics in vascular smooth muscle cells exposed to fibroblast growth factor-2 or interleukin-1β

AMN Alhendi, M Patrikakis, CO Daub, H Kawaji… - Scientific Reports, 2018 - nature.com
Smooth muscle cells (SMC) in blood vessels are normally growth quiescent and
transcriptionally inactive. Our objective was to understand promoter usage and dynamics in …

Interaction Mechanism of RGD Tripeptide on Different Surfaces of Mg and Mg Alloys: A First-Principles Study

Z Fang, H Ding, P Li, H Qiao, E Liang, Y Jia, S Guan - Coatings, 2022 - mdpi.com
Highlights The adsorption models of RGD on different surfaces of Mg and Mg alloys were set
up. Alloying elements promoted the adsorption of RGD on different Mg surfaces. The ligand …

Vascular endothelial growth factor‐modified macrophages accelerate reendothelialization and attenuate neointima formation after arterial injury in atherosclerosis …

D Yan, D Zhang, L Lu, H Qiu… - Journal of Cellular …, 2019 - Wiley Online Library
Vascular endothelial growth factor (VEGF) is a promising molecule for cardiovascular
diseases therapy. But lack of a targeted delivery system limits its translation into clinical …

Rutaecarpine inhibits intimal hyperplasia in A balloon-injured rat artery model

Y Xu, X Chen, F Zhang, H Hou, J Zhang, S Lin… - Chinese journal of …, 2018 - Springer
Objective To investigate the effect and potential mechanisms of rutaecarpine (Rut) in a rat
artery balloon-injury model. Methods The intimal hyperplasia model was established by …