Can we use biomarkers to identify those at risk of acute pain from sickle cell disease?
V Bhat, VA Sheehan - Expert Review of Hematology, 2024 - Taylor & Francis
Introduction Acute pain episodes, also known as vaso-occlusive crises (VOC), are a major
symptom of sickle cell disease (SCD) and lead to frequent hospitalizations. The diagnosis of …
symptom of sickle cell disease (SCD) and lead to frequent hospitalizations. The diagnosis of …
Δ9-Tetrahydrocannabinol Alleviates Hyperalgesia in a Humanized Mouse Model of Sickle Cell Disease
People with sickle cell disease (SCD) often experience chronic pain as well as
unpredictable episodes of acute pain, which significantly affects their quality of life and life …
unpredictable episodes of acute pain, which significantly affects their quality of life and life …
Coagulation and platelet biology at the intersection of health and disease: illustrated capsules of the 11th Symposium on Hemostasis at the University of North …
Abstract The University of North Carolina Symposia on Hemostasis began in 2002, with “The
First Symposium on Hemostasis with a Special Focus on FVIIa and Tissue Factor.” They …
First Symposium on Hemostasis with a Special Focus on FVIIa and Tissue Factor.” They …
Mast cell extracellular trap formation underlies vascular and neural injury and hyperalgesia in sickle cell disease
DA Argueta, H Tran, Y Goel, A Nguyen… - Life science …, 2024 - life-science-alliance.org
Sickle cell disease (SCD) is the most common inherited monogenetic disorder. Chronic and
acute pain are hallmark features of SCD involving neural and vascular injury and …
acute pain are hallmark features of SCD involving neural and vascular injury and …
NOVEL THERAPEUTIC APPROACHES IN THALASSEMIAS, SICKLE CELL DISEASE AND OTHER RED CELL DISORDERS
VM Pinto, F Mazzi, L De Franceschi - Blood, 2024 - Elsevier
In this last decade, a deeper understanding of the pathophysiology of hereditary red cell
disorders and the development of novel classes of pharmacologic agents have provided …
disorders and the development of novel classes of pharmacologic agents have provided …
Spleen tyrosine kinase inhibition mitigates hemin-induced thromboinflammation in the lung and kidney of sickle cell mice
J El-Awaisi, G Perrella, N Mayor, V Tinkova, SJ Cleary… - bioRxiv, 2024 - biorxiv.org
Sickle cell disease (SCD) leads to hemolytic anemia, vaso-occlusive crisis (VOC),
hypoperfusion, and progressive organ damage. Hemin, released during hemolysis in SCD …
hypoperfusion, and progressive organ damage. Hemin, released during hemolysis in SCD …
Cold comfort in sickle cell disease
E Sparkenbaugh, J Little - Blood, 2023 - ashpublications.org
In Minnesota, they must think about cold a lot. Kofi Annan said that, as a young Ghanaian
student in St. Paul, he found earmuffs“inelegant”—until it was− 23◦ F.“I learned a precious …
student in St. Paul, he found earmuffs“inelegant”—until it was− 23◦ F.“I learned a precious …