Thiazolidinediones: an in–depth study of their synthesis and application to medicinal chemistry in the treatment of diabetes mellitus

N Long, A Le Gresley, SP Wren - ChemMedChem, 2021 - Wiley Online Library
Thiazolidinedione (TZD) is a privileged and highly utilised scaffold for the development of
pharmaceutically active compounds. This sulfur‐containing heterocycle is a versatile …

Chemistry and applications of functionalized 2, 4‐thiazolidinediones

AM Ibrahim, ME Shoman… - European Journal of …, 2023 - Wiley Online Library
Thiazolidinedione (TZD) is one of the privileged heterocyclic rings and has shown many
biological applications in medicinal chemistry and drug discovery. This review covers the …

[HTML][HTML] Sonochemical activation-assisted biosynthesis of Au/Fe3O4 nanoparticles and sonocatalytic degradation of methyl orange

Á de Jesús Ruíz-Baltazar - Ultrasonics sonochemistry, 2021 - Elsevier
In this research, a sonochemical activation-assisted biosynthesis of Au/Fe 3 O 4
nanoparticles is proposed. The proposed synthesis methodology incorporates the use of …

Interfacial phenomena and surface protection of N80-carbon steel in acidic environments using thiazolidinediones: An experimental and computational analysis

AA Mansour, C Hejjaj, FZ Thari, K Karrouchi… - Colloids and Surfaces A …, 2023 - Elsevier
In petrochemical engineering, a pressing challenge is the corrosion of N80 carbon steel
(N80-CS) in strong acidic conditions like 15 wt% HCl, impacting both mechanical integrity …

Synthesis, α-glucosidase inhibition, anticancer, DFT and molecular docking investigations of pyrazole hydrazone derivatives

K Karrouchi, Y Sert, M Ansar, S Radi… - Polycyclic Aromatic …, 2023 - Taylor & Francis
In this work, three N'-arylidene-5-phenyl-1H-pyrazole-3-carbohydrazide (3a-3c), derivatives
have been synthesized and fully characterized by IR, 1H & 13C NMR and ESI-MS using …

Design, synthesis, anticancer evaluation and molecular docking studies of new imidazo [2, 1-b] thiazole -based chalcones

S Dadou, A Altay, M Koudad, B Türkmenoğlu… - Medicinal Chemistry …, 2022 - Springer
A new series of imidazo [2, 1-b] thiazole-based chalcone derivatives were designed,
synthesized, and tested for their anticancer activities. Firstly, the cytotoxic ability of the …

[HTML][HTML] Adsorption mechanism of eco-friendly corrosion inhibitors for exceptional corrosion protection of carbon steel: electrochemical and first-principles DFT …

A Chaouiki, M Chafiq, YG Ko, AH Al-Moubaraki… - Metals, 2022 - mdpi.com
In the present work, we represent two thiazolidinediones, namely (Z)-5-(4-
methoxybenzylidene) thiazolidine-2, 4-dione (MeOTZD) and (Z)-5-(4-methylbenzylidene) …

Synthesis, α-glucosidase and α-amylase inhibitory activities, acute toxicity and molecular docking studies of thiazolidine-2, 4-diones derivatives

S Fettach, FZ Thari, Z Hafidi, H Tachallait… - Journal of …, 2022 - Taylor & Francis
In the present study, a series of thiazolidine-2, 4-diones derivatives (3a–3e) and (4a–4e)
were synthesized and characterized by 1H NMR, 13C NMR and ESI-MS spectrometry. All …

[HTML][HTML] One-pot three-component synthesis of novel phenyl-pyrano-thiazol-2-one derivatives and their anti-diabetic activity studies

S Prabhakaran, N Nivetha, SM Patil, RM Martiz… - Results in …, 2022 - Elsevier
An easy and rapid synthetic approach for the synthesis of phenyl-pyrano-thiazol-2-one
derivatives using base catalysed one-pot three-component reaction between substituted …

Biological, toxicological and molecular docking evaluations of isoxazoline-thiazolidine-2, 4-dione analogues as new class of anti-hyperglycemic agents

S Fettach, FZ Thari, Z Hafidi, K Karrouchi… - Journal of …, 2023 - Taylor & Francis
In this work, three isoxazoline-thiazolidine-2, 4-dione derivatives were synthesized and
characterized by FT-IR, 1H-NMR, 13C-NMR and ESI-MS spectrometry. All compounds have …