Three-dimensional liver models: State of the art and their application for hepatotoxicity evaluation
X Zhang, T Jiang, D Chen, Q Wang… - Critical Reviews in …, 2020 - Taylor & Francis
While alternative methods for toxicity testing using re-constructed human skin and cornea
have been written into guidelines and adopted by regulatory authorities, three-dimensional …
have been written into guidelines and adopted by regulatory authorities, three-dimensional …
Compositions and methods for molecular labeling
M Samuels, JC Olson, A Watson, K Brown… - US Patent …, 2015 - Google Patents
2012-05-08 Assigned to RAINDANCE TECHNOLOGIES, INC. reassignment RAINDANCE
TECHNOLOGIES, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR …
TECHNOLOGIES, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR …
Fluorocarbon emulsion stabilizing surfactants
C Holtze, DA Weitz, JB Hutchison - US Patent 9,012,390, 2015 - Google Patents
Surfactants (eg, fluorosurfactants) for stabilizing aqueous or hydrocarbon droplets in a
fluorophilic continuous phase are presented. In some embodiments, fluorosurfactants …
fluorophilic continuous phase are presented. In some embodiments, fluorosurfactants …
Sample multiplexing
D Link - US Patent 8,841,071, 2014 - Google Patents
The invention generally relates to methods for sample multiplexing. In certain embodiments,
methods of the invention obtaining a plurality of different reactant molecules, attaching a …
methods of the invention obtaining a plurality of different reactant molecules, attaching a …
Methods for forming mixed droplets
Y Yurkovetsky, DR Link, JW Larson - US Patent 9,364,803, 2016 - Google Patents
The invention generally relates to methods for forming mixed droplets. In certain
embodiments, methods of the invention involve forming a droplet, and contacting the droplet …
embodiments, methods of the invention involve forming a droplet, and contacting the droplet …
Manipulation of microfluidic droplets
B Miller, B Hutchison, A Wilson, J Larson… - US Patent …, 2013 - Google Patents
The invention provides methods for assessing one or more predetermined characteristics or
properties of a microfluidic droplet within a microfluidic channel, and regulating one or more …
properties of a microfluidic droplet within a microfluidic channel, and regulating one or more …
In vitro evolution in microfluidic systems
AD Griffiths, DA Weitz, DR Link, K Ahn… - US Patent …, 2014 - Google Patents
The invention describes a method for isolating one or more genetic elements encoding a
gene product having a desired activity, comprising the steps of:(a) compartmentalizing …
gene product having a desired activity, comprising the steps of:(a) compartmentalizing …
Microfluidic systems and methods for reducing the exchange of molecules between droplets
F Kleinschmidt, AD Griffiths, F Caron… - US Patent …, 2020 - Google Patents
US10837883B2 - Microfluidic systems and methods for reducing the exchange of
molecules between droplets - Google Patents US10837883B2 - Microfluidic systems and …
molecules between droplets - Google Patents US10837883B2 - Microfluidic systems and …
Digital analyte analysis
JW Larson, Q Zhong, DR Link - US Patent 8,535,889, 2013 - Google Patents
The invention generally relates to droplet based digital PCR and methods for analyzing a
target nucleic acid using the same. In certain embodiments, methods of the invention involve …
target nucleic acid using the same. In certain embodiments, methods of the invention involve …
Vascularized perfused microtissue/micro-organ arrays
LG Griffith, S Tannenbaum, MJ Powers… - US Patent …, 2001 - Google Patents
Systems including (1) a micromatrix and perfusion assembly Suitable for Seeding and
attachment of cells within the matrix and for morphogenesis of Seeded cells into complex …
attachment of cells within the matrix and for morphogenesis of Seeded cells into complex …